Mittal, SunilKaur, HardeepGautam, NandiniMantha, Anil K.2017-08-212024-08-132017-08-212024-08-132017Mittal, S., Kaur, H., Gautam, N., & Mantha, A. K. (2017). Biosensors for breast cancer diagnosis: A review of bioreceptors, biotransducers and signal amplification strategies. Biosensors and Bioelectronics, 88, 217-231. doi: 10.1016/j.bios.2016.08.028956566310.1016/j.bios.2016.08.028http://10.2.3.109/handle/32116/352Breast cancer is highly prevalent in females and accounts for second highest number of deaths, worldwide. Cumbersome, expensive and time consuming detection techniques presently available for detection of breast cancer potentiates the need for development of novel, specific and ultrasensitive devices. Biosensors are the promising and selective detection devices which hold immense potential as point of care (POC) tools. Present review comprehensively scrutinizes various breast cancer biosensors developed so far and their technical evaluation with respect to efficiency and potency of selected bioreceptors and biotransducers. Use of glycoproteins, DNA biomarkers, micro-RNA, circulatory tumor cells (CTC) and some potential biomarkers are introduced briefly. The review also discusses various strategies used in signal amplification such as nanomaterials, redox mediators, p19 protein, duplex specific nucleases (DSN) and redox cycling. ? 2016 Elsevier B.V.en-USActivation AnalysisBiomarkersBiosensorsDiagnosisNanostructured MaterialsNucleic AcidsSignal ProcessingBreast CancerBreast Cancer DiagnosisDuplex-Specific NucleaseRedox CyclingRedox MediatorsSelective DetectionSignal AmplificationsTechnical EvaluationDiseasesAptamerAutoantibodyBiological MarkerBioreceptorCell Free DnaComplementary DnaDnaDuplex Specific NucleaseGlycoproteinMicrornaNanomaterialNucleaseProtein P19Quantum DotReceptorTumorArticlehttps://www.sciencedirect.com/science/article/pii/S0956566316307850?via%3Dihub