SheetalSharma, Ajay KumarShaifaliBhattacherjee, DhananjaySharma, NavneetGiri, KousikDas, Pralay2024-01-212024-08-132024-01-212024-08-132021-11-212468823110.1016/j.mcat.2021.111948https://kr.cup.edu.in/handle/32116/3302Aryl iodides as dual arylating agent for C-terminal from oxalic acid [(CO2H)2] and N-terminal from sodium azide (NaN3) for N-aryl benzamides (Ar-CO-NH-Ar) synthesis is a rare invention which has been attempted successfully under this study. A single step tandem approach for the synthesis of N-aryl benzamides has been developed through bifunctional transformation of aryl iodides with in-situ CO from (CO2H)2 and NaN3 following two different pathways of carbonylation and azidation. The polystyrene supported palladium (Pd@PS) catalyst was found to be well compatible to perform the domino-reaction in a double layer vial (DLV) system under base, ligand and additive-free conditions. Moreover, the same approach was further extended with aryl azides for unsymmetric N-aryl benzamides (Ar-CO-NH-Ar') synthesis. Furthermore, the DFT studies were also performed to support the proposed mechanism. � 2021en-USCarbonylationN-aryl benzamidesOxalic acid as CO sourcePalladium catalystSodium azideArticlehttps://linkinghub.elsevier.com/retrieve/pii/S2468823121005654