Kumar, ManvendraChatterjee, JoydeepRani, DimpyKumar, Raj2024-01-212024-08-132024-01-212024-08-132022-10-149780443186165978044318617210.1016/B978-0-443-18616-5.00006-5https://kr.cup.edu.in/handle/32116/3571Pyrimidines-based drugs are one of the most important drugs for novel and recurring viruses, including the coronavirus. This chapter deals with 41 FDA-approved five-membered ring fused pyrimidine-based drugs, their synthetic strategies, and pharmacological activities. � 2023 Elsevier Ltd. All rights reserved.en-USFDA approved drugsFive-membered ring fused pyrimidinesNucleosidesPDE5Pharmacological activitySynthesisFDA approved five-membered ring fused pyrimidine-based derivatives and their biological propertiesBook chapterhttps://linkinghub.elsevier.com/retrieve/pii/B9780443186165000065Fused Pyrimidine-Based Drug Discovery