Gupta, Harshita2018-09-062024-08-132018-09-062024-08-132018Gupta, Harshita (2018) Host-Guest Interaction of calix[4]arene derivatives with MetforminAChttp://10.2.3.109/handle/32116/1992Calix[4]arene was lower rim functionalized to furnish receptor 2-3 and 4-6, containing propyl and cyanomethoxy moieties, respectively. The receptors were characterized by FTIR, 1H and EI-MS. UV-visible studies were performed with receptor 2-6 cone (1'10-4M) upon addition of metformin (1'10-5 - 1'10-3M). Upon addition of metformin the UV-Visible absorption showed a hyperchromic shift.The 1:1 Host-Guest complexation studied by Benesi-Hildebrand equation showed a stability constant in the range 2'104 -10'104 M-1 .en-USCalix 4 areneHost-guest complexMetforminBenesi-Hildebrand equationMaster DissertationT00835