Sharma, UttamBarwal, Tushar SinghMurmu, MasangAcharya, VarnaliPant, NehaDey, DamayantiVivekGautam, AshimaBazala, SonaliSingh, IpsaAzzouz, FarahBishayee, AnupamJain, Aklank2024-01-212024-08-132024-01-212024-08-132022-02-231752036310.2217/bmm-2021-0682https://kr.cup.edu.in/handle/32116/3817Recently, long intergenic non-protein coding RNA 01133 (LINC01133) was identified as a novel transcript in cancers. It modulates various hallmarks of cancers and acts as oncogenic in some cancers while tumor-suppressive in others. Furthermore, the expression of LINC01133 correlates with tumor size, advanced tumor node metastasis stage and lymphatic node metastasis, Ki-67 levels and overall survival of patients. Herein, the authors provide an in-depth analysis describing how LINC01133 modulates the multiple cancer-associated signaling pathways and the pathogenesis of various malignancies and treatment regimens. Based on the role played by LINC01133, the authors propose LINC01133 as both a potential biomarker and a therapeutic target in cancer. � 2022 Future Medicine Ltd.en-UScancer biomarkersdiagnosisLINC01133lncRNAlong non-coding RNAprognosisReviewhttps://www.futuremedicine.com/doi/10.2217/bmm-2021-0682