Singh, HarshwardhanAnila, Kumari V. S.Singh, Ankit KumarKumar, AdarshKumar, Pradeep2024-01-212024-08-132024-01-212024-08-132023-10-111385272810.2174/0113852728264519231006055100http://10.2.3.109/handle/32116/3621Tuberculosis (TB) is the major cause of mortality around the world and one of the most common diseases linked to AIDS. Due to the emergence of multi-drug resistance, extensive drug resistance, and total drug resistance strains, TB has become a difficult disease to treat. Isoxazole scaffold shows a wide range of biological activities, including anticancer, antibacterial, anti-tubercular, antiviral, and anti-inflammatory activities etc. Several isoxazole derivatives have been produced and few of them have shown comparable anti-tubercular activity with standard drugs. In this review, we have focused on reported isoxazole derivatives having anti-tubercular activity and summarized their structure-activity relationship. � 2023 Bentham Science Publishers.en-USanti-tubercular agentsinflammatoryIsoxazolemedicinal chemistryMycobacterium tuberculosistuberculosisShort surveyhttps://www.eurekaselect.com/221932/article