Devi, NishaGupta, AntrikshGujjarappa, RaghuramMalakar, Chandi C.Singh, Virender2024-01-212024-08-132024-01-212024-08-132021-02-26385541410.3987/COM-20-14403https://kr.cup.edu.in/handle/32116/3207An efficient synthesis of o-nitrophenyl tethered pyrazole-4-carbaldehydes was achieved via Vilsmeier-Haack formylation of hydrazone derivatives which were subjected to Claisen-Schmidt condensation and Morita-Baylis-Hillman (MBH) reaction with various methyl ketones and activated alkenes respectively to generate the corresponding chalcones and MBH adducts. However, successive Fe-mediated reductive cyclization was followed by an unusual C-C bond cleavage which afforded the pyrazolo[4,3-c]quinolines devoid of diverse substituents at C-4 position. � 2021 The Japan Institute of Heterocyclic Chemistry.en-USArticlehttp://www.heterocycles.jp/newlibrary/libraries/abst/27129