Poduri, Ramarao2024-01-212024-08-132024-01-212024-08-132021-02-189789811555343978981155533610.1007/978-981-15-5534-3_17https://kr.cup.edu.in/handle/32116/3511This chapter reviews the literature on the various factors (time-consuming processes, regulatory requirements, high attrition rate in phase III clinical trials and decrease in RandD productivity) contributed to increase the average cost of drug discovery. A better interaction between the stakeholders, i.e. pharmaceutical industry, academia, regulatory authorities and end users, results in efficacious, safe and affordable drugs to the benefit of the society. � Springer Nature Singapore Pte Ltd. 2021.en-USAcademiaPatientsPharmaceutical IndustryRegulatory AuthoritiesTranslational ResearchPharmaceutical Industry, Academia, Regulatory Authorities and End User Collaboration in Successful Drug Discovery and DevelopmentBook chapterhttp://link.springer.com/10.1007/978-981-15-5534-3_17Drug Discovery and Development: From Targets and Molecules to Medicines