Rani, NidhiSingh, RandhirKumar, PraveenVerma, Nitin2024-01-212024-08-142024-01-212024-08-142023-07-112215083810.2174/2215083810666230710122114http://10.2.3.109/handle/32116/4387Background: Since ancient times, medicinal plants have been in use in medicine and daily life. Objective: To develop new antifungal compounds with low toxicity and high efficacy followed by high bioavailability, the constituents of Terminalia chebula were studied. Methods: The chemical constituents of the plant were evaluated for antifungal potential via Molergo Virtual Docker against the enzyme 14?-demethylase. Results: The study depicted that tannins exhibited very good potential against the enzyme and could be used further for lead development. Conclusion: The study revealed that the plant possessed various constituents with potential antifungal properties and low toxicity. � 2024 Bentham Science Publishers.en-US14?-demethylaseAntifungalantifungal compoundsmolecular dockingtanninsterminaliaIn Silico Study of the Structural Disruption of 14?-demethylase Induced by the Binding of Terminalia chebula ConstituentsArticlehttps://www.eurekaselect.com/218590/articleCurrent Traditional Medicine