Deep eutectic solvents with ultrasonic energy as an environmentally benign and green approach for the synthesis of bisthioglycolic acid derivatives

Kumar, GobindSingh, ParveshBhargava, GauravGill, Baljinder SinghRajput, Jaspreet KaurKumar, Rupesh2024-01-162024-08-132024-01-162024-08-132023-08-081741599310.1080/17415993.2023.2242994https://doi.org/10.1080/17415993.2023.2242994https://kr.cup.edu.in/handle/32116/2940The present methodology explored the effectiveness and versatility of deep eutectic solvent with ultrasonic energy as an eco-friendly protocol for the synthesis of bisthioglycolic acid derivatives. Bisthioglycolic moiety holds its role as a potent scaffold in sulfur-containing drugs. The presented strategy offers significant advantages such as green catalyst as well as solvent, excellent yield, short reaction time, and simple reaction workup. This methodology shows a wide range of substrate scope that contain both electron-donating as well as electron-withdrawing groups. � 2023 Informa UK Limited, trading as Taylor & Francis Group.en-USbisthioglycolic acidcarbon�sulfur bond formationdeep eutectic solventgreen chemistryUltrasonic energyDeep eutectic solvents with ultrasonic energy as an environmentally benign and green approach for the synthesis of bisthioglycolic acid derivativesArticleJournal of Sulfur Chemistry