Kumar, PuneetKumar, MandeepBedi, OnkarGupta, ManishaKumar, SachinJaiswal, GagandeepRahi, VikrantYedke, Narhari GangaramBijalwan, AnjaliSharma, ShubhamJamwal, Sumit2024-01-212024-08-142024-01-212024-08-142021-06-10925469210.1007/s10787-021-00826-7http://10.2.3.109/handle/32116/4292Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) known as coronavirus disease (COVID-19), emerged in Wuhan, China, in December 2019. On March 11, 2020, it was declared a global pandemic. As the world grapples with COVID-19 and the paucity of clinically meaningful therapies, attention has been shifted to modalities that may aid in immune system strengthening. Taking into consideration that the COVID-19 infection strongly affects the immune system via multiple inflammatory responses, pharmaceutical companies are working to develop targeted drugs and vaccines against SARS-CoV-2 COVID-19. A balanced nutritional diet may play an essential role in maintaining general wellbeing by controlling chronic infectious diseases. A balanced diet including vitamin A, B, C, D, E, and K, and some micronutrients such as zinc, sodium, potassium, calcium, chloride, and phosphorus may be beneficial in various infectious diseases. This study aimed to discuss and present recent data regarding the role of vitamins and minerals in the treatment of COVID-19. A deficiency of these vitamins and minerals in the plasma concentration may lead to a reduction in the good performance of the immune system, which is one of the constituents that lead to a poor immune state. This is a narrative review concerning the features of the COVID-19 and data related to the usage of vitamins and minerals as preventive measures to decrease the morbidity and mortality rate in patients with COVID-19. � 2021, The Author(s), under exclusive licence to Springer Nature Switzerland AG.en-USCorona virusCOVID-19MineralsTherapyVitaminReviewhttps://link.springer.com/10.1007/s10787-021-00826-7