• Login
    View Item 
    •   Knowledge Repository Home
    • School of Basic and Applied Sciences
    • Department of Pharmaceutical Sciences and Natural Products
    • Pharmaceutical Sciences and Natural Products-Research Publications
    • View Item
    •   // Knowledge Repository Home
    • // School of Basic and Applied Sciences
    • // Department of Pharmaceutical Sciences and Natural Products
    • // Pharmaceutical Sciences and Natural Products-Research Publications
    • // View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    Knowledge RepositorySchools & CollectionsBy Issue DateAuthorsTitlesSubjectsBy Submit DateThis CollectionBy Issue DateAuthorsTitlesSubjectsBy Submit Date

    My Account

    LoginRegister

    4,5-Dihydro-1H-pyrazole: An indispensable scaffold

    Thumbnail
    View/Open
    28.pdf (2.712Mb)
    Date
    2014
    Author
    Alex, Jimi Marin
    Kumar, Raj
    Metadata
    Show full item record
    Abstract
    Pyrazoles, categorized as nitrogen-containing heterocycles, are well known for their interminable participation in the field of perpetual research and development of therapeutical active agents. As a consequence pyrazoles became an inevitable core of numerous drugs having diverse activities. The broad spectrum of activities portrayed by the pyrazoles instigated the researchers to modify the pyrazole ring as 4,5-dihydro-1H-pyrazoles commonly known as 2-pyrazolines. The present review is a concerted effort to retrace compounds covered from 2009-till date which owe diverse biological activities to the 2-pyrazoline scaffold and also condenses the retro-synthetic approaches employed for their synthesis. This endeavor culminated in revelation that inhibitory potential varied when the substituents in particular N-substituents of 2-pyrazolines were altered. ? 2014 Informa UK Ltd.
    Journal
    Journal of Enzyme Inhibition and Medicinal Chemistry
    URI
    http://210.212.34.21/handle/32116/299
    URL
    https://www.tandfonline.com/doi/full/10.3109/14756366.2013.795956
    DOI
    10.3109/14756366.2013.795956
    Collections
    • Pharmaceutical Sciences and Natural Products-Research Publications [166]

    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
    Initiatives by University Library 
    Central University of Punjab
     

     


    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
    Initiatives by University Library 
    Central University of Punjab