Browsing by Author "Vaishali, None"

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    A cascade A3 coupling strategy towards the regioselective synthesis of ?-carboline N-fused pyrrole derivatives with pyridine tethers
    (Royal Society of Chemistry, 2022-12-01T00:00:00) Vaishali, None; Malakar, Chandi C.; Singh, Virender
    A potential three component reaction strategy has been devised to generate nature inspired ?-carboline N-fused pyrroles containing pyridine tethers. These scaffolds were afforded in high yields via a one-pot cascade regioselective reaction of diverse Kumujian C, 2-aminopyridines and alkyne derivatives under Cu(ii)-catalysis. A library of 32 novel indolizino[8,7-b]indole derivatives with pyridine tethers has been developed. The current protocol offers excellent regioselectivity, high atom-economy and significant structural diversity. � 2023 The Royal Society of Chemistry.