Ex vivo interaction study of NaYF4:Yb,Er nanophosphors with isolated mitochondria
| dc.contributor.author | Singh, Varun Pratap | |
| dc.contributor.author | Chawda, Nitya | |
| dc.contributor.author | Barkhade, Tejal | |
| dc.contributor.author | Mahapatra, Santosh Kumar | |
| dc.contributor.author | Banerjee, Indrani | |
| dc.date.accessioned | 2024-01-21T10:42:29Z | |
| dc.date.accessioned | 2024-08-13T12:44:31Z | |
| dc.date.available | 2024-01-21T10:42:29Z | |
| dc.date.available | 2024-08-13T12:44:31Z | |
| dc.date.issued | 2021-04-08T00:00:00 | |
| dc.description.abstract | Ex vivo interaction of NaYF4:Yb,Er nanophosphors with isolated mitochondria has been investigated. The nanophosphors were synthesized using the hydrothermal method. The synthesized NaYF4:Yb,Er nanophosphors were characterized for physicochemical properties. The NaYF4:Yb,Er nanophosphors showed successful upconversion with excitation wavelength lying in the near-infrared region. The effect of synthesized NaYF4:Yb,Er nanophosphors on mitochondria isolated from the chicken heart tissue was examined through ROS generation capacity, membrane fluidity, and complex II activity. The exposer of NaYF4:Yb,Er nanophosphors to isolated mitochondria inhibits ROS generation activity as compared to control. The mitochondria membrane fluidity of the lipid bilayer and complex-II activity of mitochondria was observed to be unaltered after the interaction with NaYF4:Yb,Er nanoparticles. The results confirm that synthesized NaYF4:Yb,Er nanoparticles can be used as a safe contrast agent. � 2021 International Union of Biochemistry and Molecular Biology, Inc. | en_US |
| dc.identifier.doi | 10.1002/bab.2163 | |
| dc.identifier.issn | 8854513 | |
| dc.identifier.uri | https://kr.cup.edu.in/handle/32116/3649 | |
| dc.identifier.url | https://iubmb.onlinelibrary.wiley.com/doi/10.1002/bab.2163 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | John Wiley and Sons Inc | en_US |
| dc.subject | fluidity | en_US |
| dc.subject | mitochondria | en_US |
| dc.subject | organelles | en_US |
| dc.subject | reactive oxygen species (ROS) generation | en_US |
| dc.subject | upconversion nanoparticles | en_US |
| dc.title | Ex vivo interaction study of NaYF4:Yb,Er nanophosphors with isolated mitochondria | en_US |
| dc.title.journal | Biotechnology and Applied Biochemistry | en_US |
| dc.type | Article | en_US |
| dc.type.accesstype | Closed Access | en_US |