An Overview on Biological Activities of Oxazole, Isoxazoles and 1,2,4-Oxadiazoles Derivatives

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dc.contributor.authorGujjarappa, Raghuram
dc.contributor.authorSravani, Sattu
dc.contributor.authorKabi, Arup K.
dc.contributor.authorGarg, Aakriti
dc.contributor.authorVodnala, Nagaraju
dc.contributor.authorTyagi, Ujjawal
dc.contributor.authorKaldhi, Dhananjaya
dc.contributor.authorSingh, Virender
dc.contributor.authorGupta, Sreya
dc.contributor.authorMalakar, Chandi C.
dc.date.accessioned2024-01-21T10:32:59Z
dc.date.accessioned2024-08-13T11:16:42Z
dc.date.available2024-01-21T10:32:59Z
dc.date.available2024-08-13T11:16:42Z
dc.date.issued2022-03-07T00:00:00
dc.description.abstractHeterocyclic compounds containing the oxazole, isoxazole and oxadiazoles rings have received significant consideration as they perform like a link between life sciences and chemical sciences. In the past few years, the efficacy of these heterocyclic nuclei as synthetic intermediates for the development of novel chemical entities in medicinal and pharmaceutical chemistry has enhanced worldwide. Moreover, the importance of N-heterocycles from a medicinal point of view is due to their readily binding ability with biological systems such as various enzymes and receptors via numerous non-covalent interactions. Globally, similar research of finding Oxazole-based derivatives as potent medicinal drug candidates is an active topic which includes; oxazoles, isoxazoles, oxadiazoles, benzoxazoles, oxazolines, oxazolidinones, etc., in the study. Prominently, plenty of oxazole-based molecular scaffolds as active pharmacophores have been used against various diseases, which has shown their importance for the development as potential pharmaceutical agents. This chapter thoroughly highlights the current developments and researches involving; oxazole, isoxazole and oxadiazole-based compounds as clinical candidates, including anticancer, antibacterial, antiviral, antifungal, anti-inflammatory and antitubercular, antidiabetic as well as other biological activities. � 2022, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.en_US
dc.identifier.doi10.1007/978-981-16-8399-2_10
dc.identifier.issn25245384
dc.identifier.urihttp://10.2.3.109/handle/32116/3233
dc.identifier.urlhttps://link.springer.com/10.1007/978-981-16-8399-2_10
dc.language.isoen_USen_US
dc.publisherSpringer Natureen_US
dc.subjectDrug Discoveryen_US
dc.subjectIsoxazolesen_US
dc.subjectOxadiazolesen_US
dc.subjectOxazolesen_US
dc.subjectPharmacophoreen_US
dc.titleAn Overview on Biological Activities of Oxazole, Isoxazoles and 1,2,4-Oxadiazoles Derivativesen_US
dc.title.journalMaterials Horizons: From Nature to Nanomaterialsen_US
dc.typeBook chapteren_US
dc.type.accesstypeClosed Accessen_US

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