Biosensors for breast cancer diagnosis: A review of bioreceptors, biotransducers and signal amplification strategies

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dc.contributor.authorMittal, Sunil
dc.contributor.authorKaur, Hardeep
dc.contributor.authorGautam, Nandini
dc.contributor.authorMantha, Anil K.
dc.date.accessioned2017-08-21T09:00:22Z
dc.date.accessioned2024-08-13T13:22:06Z
dc.date.available2017-08-21T09:00:22Z
dc.date.available2024-08-13T13:22:06Z
dc.date.issued2017
dc.description.abstractBreast cancer is highly prevalent in females and accounts for second highest number of deaths, worldwide. Cumbersome, expensive and time consuming detection techniques presently available for detection of breast cancer potentiates the need for development of novel, specific and ultrasensitive devices. Biosensors are the promising and selective detection devices which hold immense potential as point of care (POC) tools. Present review comprehensively scrutinizes various breast cancer biosensors developed so far and their technical evaluation with respect to efficiency and potency of selected bioreceptors and biotransducers. Use of glycoproteins, DNA biomarkers, micro-RNA, circulatory tumor cells (CTC) and some potential biomarkers are introduced briefly. The review also discusses various strategies used in signal amplification such as nanomaterials, redox mediators, p19 protein, duplex specific nucleases (DSN) and redox cycling. ? 2016 Elsevier B.V.en_US
dc.identifier.citationMittal, S., Kaur, H., Gautam, N., & Mantha, A. K. (2017). Biosensors for breast cancer diagnosis: A review of bioreceptors, biotransducers and signal amplification strategies. Biosensors and Bioelectronics, 88, 217-231. doi: 10.1016/j.bios.2016.08.028en_US
dc.identifier.doi10.1016/j.bios.2016.08.028
dc.identifier.issn9565663
dc.identifier.urihttp://10.2.3.109/handle/32116/352
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S0956566316307850?via%3Dihub
dc.language.isoen_USen_US
dc.publisherElsevier Ltden_US
dc.subjectActivation Analysisen_US
dc.subjectBiomarkersen_US
dc.subjectBiosensorsen_US
dc.subjectDiagnosisen_US
dc.subjectNanostructured Materialsen_US
dc.subjectNucleic Acidsen_US
dc.subjectSignal Processingen_US
dc.subjectBreast Canceren_US
dc.subjectBreast Cancer Diagnosisen_US
dc.subjectDuplex-Specific Nucleaseen_US
dc.subjectRedox Cyclingen_US
dc.subjectRedox Mediatorsen_US
dc.subjectSelective Detectionen_US
dc.subjectSignal Amplificationsen_US
dc.subjectTechnical Evaluationen_US
dc.subjectDiseasesen_US
dc.subjectAptameren_US
dc.subjectAutoantibodyen_US
dc.subjectBiological Markeren_US
dc.subjectBioreceptoren_US
dc.subjectCell Free Dnaen_US
dc.subjectComplementary Dnaen_US
dc.subjectDnaen_US
dc.subjectDuplex Specific Nucleaseen_US
dc.subjectGlycoproteinen_US
dc.subjectMicrornaen_US
dc.subjectNanomaterialen_US
dc.subjectNucleaseen_US
dc.subjectProtein P19en_US
dc.subjectQuantum Doten_US
dc.subjectReceptoren_US
dc.subjectTumoren_US
dc.titleBiosensors for breast cancer diagnosis: A review of bioreceptors, biotransducers and signal amplification strategiesen_US
dc.title.journalBiosensors and Bioelectronicsen_US
dc.typeArticleen_US

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