Role of immune system in tumor progression and carcinogenesis

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dc.contributor.authorUpadhyay, S.
dc.contributor.authorSharma, N.
dc.contributor.authorGupta, K.B.
dc.contributor.authorDhiman, M.
dc.date.accessioned2018-07-14T01:19:09Z
dc.date.accessioned2024-08-13T10:34:31Z
dc.date.available2018-07-14T01:19:09Z
dc.date.available2024-08-13T10:34:31Z
dc.date.issued2018
dc.description.abstractTumor micro-environment has potential to customize the behavior of the immune cell according to their need. In immune-eliminating phase, immune cells eliminate transformed cells but after tumor establishment innate and adaptive immune cells synergistically provide shelter as well as fulfill their requirement that helps in progression. In between eliminating and establishment phase, equilibrium and escaping phase regulate the immune cells response. During immune-escaping, (1) the antigenic response generated is either inadequate, or focused entirely on tolerance, and (2) immune response generated is specific and effective, but the tumor skips immune recognition. In this review, we are discussing the critical role of immune cells and their cytokines before and after the establishment of tumor which might play a critical role during immunotherapy. ? 2018 Wiley Periodicals, Inc.en_US
dc.identifier.citationUpadhyay, S., Sharma, N., Gupta, K. B., & Dhiman, M. (2018). Role of immune system in tumor progression and carcinogenesis. Journal of Cellular Biochemistry, 119(7), 5028-5042. doi: 10.1002/jcb.26663en_US
dc.identifier.doi10.1002/jcb.26663
dc.identifier.issn7302312
dc.identifier.urihttp://10.2.3.109/handle/32116/1458
dc.identifier.urlhttps://onlinelibrary.wiley.com/doi/abs/10.1002/jcb.26663
dc.language.isoen_USen_US
dc.publisherWiley-Liss Inc.en_US
dc.subjectChemokineen_US
dc.subjectCytokineen_US
dc.subjectTumor antigenen_US
dc.subjectAdaptive immunity carcinogenesisen_US
dc.subjectDendritic cellen_US
dc.subjectHumanen_US
dc.subjectImmune systemen_US
dc.subjectImmunityen_US
dc.subjectImmunocompetent cellen_US
dc.subjectImmunosurveillanceen_US
dc.subjectImmunotherapyen_US
dc.subjectInnate immunityen_US
dc.subjectMacrophageen_US
dc.subjectMalignant neoplasmen_US
dc.subjectNatural killer cellen_US
dc.subjectNatural killer T cellen_US
dc.subjectNeutrophilen_US
dc.subjectNon humanen_US
dc.subjectPriority journalen_US
dc.subjectT lymphocyteen_US
dc.subjectTumor growthen_US
dc.subjectTumor microenvironmenten_US
dc.titleRole of immune system in tumor progression and carcinogenesisen_US
dc.title.journalJournal of Cellular Biochemistry
dc.typeArticleen_US

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