To study the effects of insulin and metformin on pc-3 cell line

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dc.contributor.authorSingh, Pushpendra
dc.contributor.supervisorBast, Felix
dc.date.accessioned2018-08-30T06:07:51Z
dc.date.accessioned2024-08-13T10:50:34Z
dc.date.available2018-08-30T06:07:51Z
dc.date.available2024-08-13T10:50:34Z
dc.date.issued2016
dc.description.abstractDietary habits, genetic factors, hormonal factors and environmental factors are the independent risk factors for prostate cancer as well as diabetes. Androgen is the primary growth factor for the prostate cancer initiation and progression, however, non androgen peptide growth factor like insulin and insulin growth factor also involved in the prostate cancer as well as diabetes. Insulin and insulin growth factor are peptide that regulates metabolism, growth, cellular proliferation and apoptosis. The anti-diabetic drug metformin is rapidly emerging as a potential anti-cancer agent that improves insulin homeostasis and decreased growth and cellular proliferation of the prostate cancer cell line. Thus it is necessary to understand the growth promoting role of insulin on prostate cancer cell line and the possible influences of metformin on the proliferation of prostate cancer cell line in the presence and absence of insulin has been studied.en_US
dc.identifier.accessionnoT00001
dc.identifier.citationSingh, Pushpendra (2016) To study the effects of insulin and metformin on pc-3 cell lineen_US
dc.identifier.urihttp://10.2.3.109/handle/32116/1722
dc.language.isoen_USen_US
dc.publisherCentral University of Punjaben_US
dc.subjectInsulinen_US
dc.subjectMetformin and Prostate Canceren_US
dc.subjectMetformin and Prostate Cancer (PC-3) cell lineen_US
dc.titleTo study the effects of insulin and metformin on pc-3 cell lineen_US
dc.typeMphil Dissertationen_US

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