Self assembled monolayer based liquid crystal biosensor for free cholesterol detection

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dc.contributor.authorTyagi, M.
dc.contributor.authorChandran, A.
dc.contributor.authorJoshi, T.
dc.contributor.authorPrakash, J.
dc.contributor.authorAgrawal, V.V.
dc.contributor.authorBiradar, A.M.
dc.date.accessioned2018-01-10T09:07:12Z
dc.date.accessioned2024-08-13T12:45:36Z
dc.date.available2018-01-10T09:07:12Z
dc.date.available2024-08-13T12:45:36Z
dc.date.issued2014
dc.date.issued2014
dc.description.abstractA unique cholesterol oxidase (ChOx) liquid crystal (LC) biosensor, based on the disruption of orientation in LCs, is developed for cholesterol detection. A self-assembled monolayer (SAM) of Dimethyloctadecyl[3-(trimethoxysilyl)propyl] ammonium chloride (DMOAP) and (3-Aminopropyl)trimethoxy-silane (APTMS) is prepared on a glass plate by adsorption. The enzyme (ChOx) is immobilized on SAM surface for 12 h before utilizing the film for biosensing purpose. LC based biosensing study is conducted on SAM/ChOx/LC (5CB) cells for cholesterol concentrations ranging from 10mg/dl to 250 mg/dl. The sensing mechanism has been verified through polarizing optical microscopy, scanning electron microscopy, and spectrometric techniques. ? 2014 AIP Publishing LLC.en_US
dc.identifier.citationTyagi, M., Chandran, A., Joshi, T., Prakash, J., Agrawal, V. V., & Biradar, A. M. (2014). Self assembled monolayer based liquid crystal biosensor for free cholesterol detection. Applied Physics Letters, 104(15). doi: 10.1063/1.4871704en_US
dc.identifier.doi10.1063/1.4871704
dc.identifier.issnPrint- 0003-6951
dc.identifier.issnOnline- 1077-3118
dc.identifier.issn36951
dc.identifier.urihttps://kr.cup.edu.in/handle/32116/538
dc.identifier.urlhttps://aip.scitation.org/doi/10.1063/1.4871704
dc.language.isoenen_US
dc.publisherAmerican Institute of Physics Inc.en_US
dc.subjectChlorine compoundsen_US
dc.subjectCholesterolen_US
dc.subjectLiquid crystalsen_US
dc.subjectScanning electron microscopyen_US
dc.subjectSelf assembled monolayersen_US
dc.subjectAmmonium chlorideen_US
dc.subjectCholesterol detectionen_US
dc.subjectCholesterol oxidaseen_US
dc.subjectFree cholesterolsen_US
dc.subjectLiquid crystal biosensorsen_US
dc.subjectPolarizing optical microscopyen_US
dc.subjectSensing mechanismen_US
dc.subjectSpectrometric techniquesen_US
dc.subjectBiosensorsen_US
dc.titleSelf assembled monolayer based liquid crystal biosensor for free cholesterol detectionen_US
dc.title.journalApplied Physics Letters
dc.typeArticleen_US

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