Browsing by Title
Now showing items 1219-1238 of 1673
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Radiation resistance: Cancer stem cells (CSCs) and their enigmatic pro-survival signaling
(Academic Press, 2015)Despite the fact that radiation therapy is a highly effective therapeutic approach, a small intratumoral cell subpopulation known as "cancer stem cells" (CSCs) is radiation-resistant and possesses specific molecular ... -
Rational design of drug-like compounds targeting Mycobacterium marinum MelF protein
(Public Library of Science, 2017)The mycobacterial mel2 locus (mycobacterial enhanced infection locus, Rv1936-1941) is Mycobacterium marinum and M. tuberculosis specific, which can withstand reactive oxygen species (ROS) and reactive nitrogen species (RNS) ... -
Re-complicating identity in Mohsin Hamid's The Reluctant Fundamentalist
(Public Knowledge Project, 2015)At the heart of a person's life lies the struggle to define his self, to make sense of who he is? Diaspora represents the settling as well as unsettling process. While redesigning the geopolitical boundaries, cultural ... -
Re-Vision of Myths In Post-Colonial Indian English Drama As An Avenue For The Empowerment Of Women
(Public Knowledge Project, 2018)Literature is one of the devices of articulating culture whereby culture gets recognised through the adaptation of myths. The revision of myths has received unparalleled recognition as a discourse through which identity ... -
Reactive Oxygen Species: Generation, Damage, and Quenching in Plants During Stress
(John Wiley & Sons Ltd, 2018)Reactive oxygen species (ROS) are reactive molecules formed during the normal metabolism of plants such as superoxide radical, hydrogen peroxide, hydroxyl radicals and singlet oxygen. They function as important signalling ... -
Readings on constructivism: Areas of practice and way forward in teaching-learning
(Mittal publications, New Delhi, India, 2018) -
Realistic attributes of punjabi society: A critique of Ajmer Singh Aulakh's plays
(Global English-Oriented Research Journal (GEORJ), 2015)This paper deals with Punjabi Playwright Ajmer Singh Aulakh's plays which illustrate the realistic features of the Punjabi society. Most of his plays are concerned with the period of Green Revolution and present contemporary ... -
Recent advancement to target Breast Cancer and Cancer Stem Cells
(Open Access, 2017)Breast cancer is the second most prominent reason of cancer death in women after lung cancer, and it accounts for 25.2% of all cancer in women [1]. In the US, approximately about one in eight women (12%) develop invasive ... -
Recent advancements in mechanistic studies and structure activity relationship of FoF1 ATP synthase inhibitor as antimicrobial agent
(Elsevier Masson SAS, 2019)The emergence of drug resistance in infectious microbial strains can be overcome by development of novel drug molecules against unexploited microbial target. The success of Bedaquiline in recent years, as FoF1 ATP synthase ... -
Recent advancements in small molecule inhibitors of insulin-like growth factor-1 receptor (IGF-1R) tyrosine kinase as anticancer agents
(2013)Advancements in understanding of the genetics, genomics, biochemistry and the pharmacology of cancer in human, have driven the current cancer chemotherapy to intently focus on development of target-based approaches rather ... -
Recent Advancements in Small Molecule Inhibitors of Insulin–like Growth Factor-1 Receptor (IGF-1R) Tyrosine Kinase as Anticancer agents
(Bentham Science, 2013)Advancements in understanding of the genetics, genomics, biochemistry and the pharmacology of cancer in human, have driven the current cancer chemotherapy to intently focus on development of target-based approaches rather ... -
Recent advances in decarboxylative C-C bond formation using direct or in situ generated alkenyl acids
(Taylor and Francis Inc., 2019)In recent years, the reactions of abundantly available, inexpensive, and structurally diverse alkenyl acids (-C=C-COOH) with C-X (X�=�halogen) or C-H coupling partner have emerged as vital strategies for the streamlined ... -
Recent advances in HER2 positive breast cancer epigenetics: Susceptibility and therapeutic strategies
(Elsevier Masson SAS, 2017)HER2 amplification/overexpression accounts for aggressive clinical features of HER2 positive breast cancer. Epigenetic changes including DNA methylation, histone modifications and ncRNAs/miRNAs are associated with regulation ... -
Recent Advances in Plant Metabolites Analysis, Isolation, and Characterization
(Springer, 2018)Metabolites from natural sources either from terrestrial or marine sources serve as unmatched resources for new drug leads or diverse chemical identity. Due to ever-rising requirement for new pharmacophore in high-throughput ... -
Recent development in indole derivatives as anticancer agents for breast cancer
(Bentham Science Publishers, 2019)Background: Breast Cancer (BC) is the second most common cause of cancer related deaths in women. Due to severe side effects and multidrug resistance, current therapies like hormonal therapy, surgery, radiotherapy and ... -
Recent developments of C-4 substituted coumarin derivatives as anticancer agents
(Elsevier Masson SAS, 2016)Cancer is a prominent cause of death in global. Currently, the numbers of drugs that are in clinical practice are having a high prevalence of side effect and multidrug resistance. Researchers have made an attempt to expand ... -
Recent developments on 1,2,4-triazole nucleus in anticancer compounds: A review
(Bentham Science Publishers B.V., 2016)1,2,4 triazole is an important nucleus present in a large number of compounds. More than thirty-five compounds containing this nucleus are introduced into the market. 1,2,4-triazole nucleus is stable to metabolism and acts ... -
Recent developments on the structure–activity relationship studies of MAO inhibitors and their role in different neurological disorders
(Royal Society of Chemistry, 2016)Monoamine oxidase (MAO) enzyme catalyzes the oxidative deamination of xenobiotic and endogenous amines including many neurotransmitters. The MAO enzyme exists in two isoforms; MAO-A and MAO-B and these isoforms display ... -
Recent synthetic strategies for monocyclic azole nucleus and its role in drug discovery and development
(Bentham Science Publishers B.V., 2018)Background: In recent years, the development and diversification of heterocyclic compounds has become central to the discovery of bioactive compounds with novel or improved pharmacological properties. In particular, ... -
Recent Trends and Advancements in Agricultural Research: An Overview
(Society of Pharmacognosy and Phytochemistry, 2018)Do you know the most precious thing happening in Indian Agriculture? Few keywords such as food, organic farming, climate change and improved farming techniques may strike to your mind. But the recent improvements in ...
