Browsing by Author "Iyer, Mahalaxmi"

Now showing items 1-10 of 10

    • Advantages of mesenchymal stem cell over the other stem cells 

      Gopalarethinam, Janani; Nair, Aswathy P.; Iyer, Mahalaxmi; Vellingiri, Balachandar; Subramaniam, Mohana Devi (Elsevier GmbH, 2023-05-09)
      A stem cell is a particular group of cells that has the extraordinary potential to convert within the body into particular cell types. They are used to regenerate tissues and cells in the body that have been damaged or ...

    • Artificial intelligence in heavy metals detection: Methodological and ethical challenges 

      Yadav, Nidhi; Maurya, Brij Mohan; Chettri, Dewan; Pooja; Pulwani, Chirag; Jajula, Mahesh; kanda, Savleen Singh; babu, Harysh Winster Suresh; Elangovan, Ajay; Velusamy, Parthasarathy; Iyer, Mahalaxmi; Vellingiri, Balachandar (Elsevier B.V., 2023-07-02)
      Heavy metals (HMs) are metallic substances. They enter biotic and abiotic systems through natural and human activities. These HMs have an impact on the atmosphere, soil, and groundwater, and they also affect all living ...

    • Assessment of tRNAThr and tRNAGln Variants and Mitochondrial Functionality in Parkinson�s Disease (PD) Patients of Tamil Nadu Population 

      Venkatesan, Dhivya; Iyer, Mahalaxmi; Raj, Neethu; Gopalakrishnan, Abilash Valsala; Narayanasamy, Arul; Kumar, Nachimuthu Senthil; Vellingiri, Balachandar (Springer, 2023-10-17)
      Parkinson�s disease (PD) is speculated with genetic and environmental factors. At molecular level, the mitochondrial impact is stated to be one of the causative reasons for PD. In this study, we investigated the mitochondrial ...

    • Concurrent Assessment of Oxidative Stress and MT-ATP6 Gene Profiling to Facilitate Diagnosis of Autism Spectrum Disorder (ASD) in Tamil Nadu Population 

      Vellingiri, Balachandar; Venkatesan, Dhivya; Iyer, Mahalaxmi; Mohan, Gomathi; Krishnan, Padmavathi; Sai Krishna, Krothapalli; Sangeetha, R.; Narayanasamy, Arul; Gopalakrishnan, Abilash Valsala; Kumar, Nachimuthu Senthil; Subramaniam, Mohana Devi (Springer, 2023-03-27)
      Autism spectrum disorder (ASD) is a neurodevelopmental disability that causes social impairment, debilitated verbal or nonverbal conversation, and restricted/repeated behavior. Recent research reveals that mitochondrial ...

    • miRNA in Parkinson's disease:�From pathogenesis to theranostic approaches 

      Elangovan, Ajay; Venkatesan, Dhivya; Selvaraj, Priyanka; Pasha, Md. Younus; Babu, Harysh Winster Suresh; Iyer, Mahalaxmi; Narayanasamy, Arul; Subramaniam, Mohana Devi; Valsala Gopalakrishnan, Abilash; Kumar, Nachimuthu Senthil; Vellingiri, Balachandar (John Wiley and Sons Inc, 2022-12-11)
      Parkinson's disease (PD) is an age associated neurological disorder which is specified by cardinal motor symptoms such as tremor, stiffness, bradykinesia, postural instability, and non-motor symptoms. Dopaminergic neurons ...

    • Plausible Role of Mitochondrial DNA Copy Number in Neurodegeneration�a Need for Therapeutic Approach in Parkinson�s Disease (PD) 

      Venkatesan, Dhivya; Iyer, Mahalaxmi; Narayanasamy, Arul; Gopalakrishnan, Abilash Valsala; Vellingiri, Balachandar (Springer, 2023-07-31)
      Parkinson�s disease (PD) is an advancing age-associated progressive brain disorder which has various diverse factors, among them mitochondrial dysfunction involves in dopaminergic (DA) degeneration. Aging causes a rise in ...

    • A review of chromium (Cr) epigenetic toxicity and health hazards 

      Iyer, Mahalaxmi; Anand, Uttpal; Thiruvenkataswamy, Saranya; Babu, Harysh Winster Suresh; Narayanasamy, Arul; Prajapati, Vijay Kumar; Tiwari, Chandan Kumar; Gopalakrishnan, Abilash Valsala; Bontempi, Elza; Sonne, Christian; Barcel�, Dami�; Vellingiri, Balachandar (Elsevier B.V., 2023-04-17)
      Carcinogenic metals affect a variety of cellular processes, causing oxidative stress and cancer. The widespread distribution of these metals caused by industrial, residential, agricultural, medical, and technical activities ...

    • Role of Telomeres and Telomerase in Parkinson's Disease�A New Theranostics? 

      Vellingiri, Balachandar; Balasubramani, Kiruthika; Iyer, Mahalaxmi; Raj, Neethu; Elangovan, Ajay; Song, Kwonwoo; Yeo, Han-Cheol; Jayakumar, Namitha; Kinoshita, Masako; Thangarasu, Ravimanickam; Narayanasamy, Arul; Dayem, Ahmed Abdal; Prajapati, Vijay Kumar; Gopalakrishnan, Abilash Valsala; Cho, Ssang-Goo (John Wiley and Sons Inc, 2023-08-21)
      Parkinson's disease (PD) is a complex condition that is significantly influenced by oxidative stress and inflammation. It is also suggested that telomere shortening (TS) is regulated by oxidative stress which leads to ...

    • Type 2 Diabetes (T2DM) and Parkinson�s Disease (PD): a Mechanistic Approach 

      Sabari, S. Sri; Balasubramani, Kiruthika; Iyer, Mahalaxmi; Sureshbabu, Harysh Winster; Venkatesan, Dhivya; Gopalakrishnan, Abilash Valsala; Narayanaswamy, Arul; Senthil Kumar, Nachimuthu; Vellingiri, Balachandar (Springer, 2023-04-28)
      Growing evidence suggest that there is a connection between Parkinson�s disease (PD) and insulin dysregulation in the brain, whilst the connection between PD and type 2 diabetes mellitus (T2DM) is still up for debate. ...

    • Untangle the mystery behind DS-associated AD � Is APP the main protagonist? 

      Elangovan, Ajay; Babu, Harysh Winster Suresh; Iyer, Mahalaxmi; Gopalakrishnan, Abilash Valsala; Vellingiri, Balachandar (Elsevier Ireland Ltd, 2023-04-07)
      Amyloid precursor protein profusion in Trisomy 21, also called Down Syndrome (DS), is rooted in the genetic determination of Alzheimer's disease (AD). With the recent development in patient care, the life expectancy of DS ...