Browsing by Author "Wander, Gurpreet S."

Now showing items 1-3 of 3

    • APOC3 genetic variation, serum triglycerides, and risk of coronary artery disease in Asian Indians, Europeans, and other ethnic groups 

      Goyal, Shiwali; Tanigawa, Yosuke; Zhang, Weihua; Chai, Jin-Fang; Almeida, Marcio; Sim, Xueling; Lerner, Megan; Chainakul, Juliane; Ramiu, Jonathan Garcia; Seraphin, Chanel; Apple, Blair; Vaughan, April; Muniu, James; Peralta, Juan; Lehman, Donna M.; Ralhan, Sarju; Wander, Gurpreet S.; Singh, Jai Rup; Mehra, Narinder K.; Sidorov, Evgeny; Peyton, Marvin D.; Blackett, Piers R.; Curran, Joanne E.; Tai, E. Shyong; van Dam, Rob; Cheng, Ching-Yu; Duggirala, Ravindranath; Blangero, John; Chambers, John C.; Sabanayagam, Charumathi; Kooner, Jaspal S.; Rivas, Manuel A.; Aston, Christopher E.; Sanghera, Dharambir K. (BioMed Central Ltd, 2021-09-21)
      Background: Hypertriglyceridemia has emerged as a critical coronary artery disease (CAD) risk factor. Rare loss-of-function (LoF) variants in apolipoprotein C-III have been reported to reduce triglycerides (TG) and are ...

    • A Bidirectional Mendelian Randomization Study to evaluate the causal role of reduced blood vitamin D levels with type 2 diabetes risk in South Asians and Europeans 

      Bejar, Cynthia A.; Goyal, Shiwali; Afzal, Shoaib; Mangino, Massimo; Zhou, Ang; van der Most, Peter J.; Bao, Yanchun; Gupta, Vipin; Smart, Melissa C.; Walia, Gagandeep K.; Verweij, Niek; Power, Christine; Prabhakaran, Dorairaj; Singh, Jai Rup; Mehra, Narinder K.; Wander, Gurpreet S.; Ralhan, Sarju; Kinra, Sanjay; Kumari, Meena; de Borst, Martin H.; Hypp�nen, Elina; Spector, Tim D.; Nordestgaard, B�rge G.; Blackett, Piers R.; Sanghera, Dharambir K. (BioMed Central Ltd, 2021-07-27)
      Context: Multiple observational studies have reported aninverse relationship between 25-hydroxyvitaminD concentrations (25(OH)D) and type 2 diabetes (T2D). However, the results ofshort- and long-term interventional trials ...

    • Burden of Type 2 Diabetes and Associated Cardiometabolic Traits and Their Heritability Estimates in Endogamous Ethnic Groups of India: Findings From the INDIGENIUS Consortium 

      Venkatesan, Vettriselvi; Lopez-Alvarenga, Juan Carlos; Arya, Rector; Ramu, Deepika; Koshy, Teena; Ravichandran, Umarani; Ponnala, Amaresh Reddy; Sharma, Surendra K.; Lodha, Sailesh; Sharma, Krishna K.; Shaik, Mahaboob Vali; Resendez, Roy G.; Venugopal, Priyanka; Parthasarathy, R.; Saju, Noelta; Ezeilo, Juliet A.; Bejar, Cynthia; Wander, Gurpreet S.; Ralhan, Sarju; Singh, Jai Rup; Mehra, Narinder K.; Vadlamudi, Raghavendra Rao; Almeida, Marcio; Mummidi, Srinivas; Natesan, Chidambaram; Blangero, John; Medicherla, Krishna M.; Thanikachalam, Sadagopan; Panchatcharam, Thyagarajan Sadras; Kandregula, Dileep Kumar; Gupta, Rajeev; Sanghera, Dharambir K.; Duggirala, Ravindranath; Paul, Solomon F. D. (Frontiers Media S.A., 2022-04-14)
      To assess the burden of type 2 diabetes (T2D) and its genetic profile in endogamous populations of India given the paucity of data, we aimed to determine the prevalence of T2D and estimate its heritability using family-based ...