Browsing by Subject "Breast Cancer"
Now showing items 1-10 of 11
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Asparagus racemosus (Shatavari) targeting estrogen receptor a: - An in-vitro and in-silico mechanistic study
(Taylor and Francis Ltd., 2018)Breast cancer is a disease where cells in the tissue of the breast, grow and divide without normal control. Breast cancer is second major cause for death in world wide. Importance of natural product increase due to adverse ... -
Biosensors for breast cancer diagnosis: A review of bioreceptors, biotransducers and signal amplification strategies
(Elsevier Ltd, 2017)Breast cancer is highly prevalent in females and accounts for second highest number of deaths, worldwide. Cumbersome, expensive and time consuming detection techniques presently available for detection of breast cancer ... -
The creation of selenium nanoparticles decorated with troxerutin and their ability to adapt to the tumour microenvironment have therapeutic implications for triple-negative breast cancer
(Royal Society of Chemistry, 2023-02-09)Despite advancements in treatment, managing aggressive types of breast cancer, particularly Triple Negative Breast Cancer (TNBC), remains a daunting task. Newer chemotherapeutics enhance the multidrug resistance in cancer ... -
Drug target strategies in breast cancer treatment: Recent developments
(Bentham Science Publishers B.V., 2014)Breast cancer (BC) is the leading cause of death among women all over the world. Estrogen receptor (ER) based therapy is one of the major approaches to target BC and is associated with various problems such as primary as ... -
Evaluation of breast cancer cell lines (MCF-7 & T47D) : Influence of insulin and metformin on growth parameters
(Central University of Punjab, 2016)Breast cancer is the complex and heterogenous malignancy caused as a result of interaction of hormonal, environmental and genetic factors. Major advances made in the field of breast cancer research have emanated from studies ... -
Expression of CHAC1 in Breast Cancer Cell Lines
(Central University of Punjab, 2018)Breast cancer is the commonly diagnosed type of cancer in women and is a major cause of deaths in women. Unfolded Protein Response Pathway is a signaling pathway induced in endoplasmic reticulum as a stress response. This ... -
Expression of KIBRA in Breast Cancer Cell Lines
(Central University of Punjab, 2018)Breast cancer the most frequently diagnosed cancer and its metastasis to distant organs accounts the majority of deaths. Numerous genes and proteins are involved in the cause of metastasis. Though KIBRA is one of the ... -
Frequency of pathogenic germline mutations in cancer susceptibility genes in breast cancer patients
(Humana Press Inc., 2018)In this study, we evaluated the incidence of pathogenic germline mutations in 30 breast cancer susceptibility genes in breast cancer patients. Our aim was to understand the involvement of the inherited mutations in these ... -
KIBRA Team Up with Partners to Promote Breast Cancer Metastasis
(Springer, 2019)Among women, breast cancer is the most frequently diagnosed cancer. Most of the breast cancers represent metastasis to distant organs at the time of diagnosis and accounts for the majority of deaths. Metastasis is characterized ... -
The regulatory roles of long non-coding RNAs in the development of chemoresistance in breast cancer
(Impact Journals LLC, 2017)Chemoresistance is one of the major hurdles in the treatment of breast cancer, which limits the effect of both targeted and conventional therapies in clinical settings. Therefore, understanding the mechanisms underpinning ...