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Concurrent Assessment of Oxidative Stress and MT-ATP6 Gene Profiling to Facilitate Diagnosis of Autism Spectrum Disorder (ASD) in Tamil Nadu Population
(Springer, 2023-03-27)
Autism spectrum disorder (ASD) is a neurodevelopmental disability that causes social impairment, debilitated verbal or nonverbal conversation, and restricted/repeated behavior. Recent research reveals that mitochondrial ...
Type 2 Diabetes (T2DM) and Parkinson�s Disease (PD): a Mechanistic Approach
(Springer, 2023-04-28)
Growing evidence suggest that there is a connection between Parkinson�s disease (PD) and insulin dysregulation in the brain, whilst the connection between PD and type 2 diabetes mellitus (T2DM) is still up for debate. ...
Evolving strategies and application of proteins and peptide therapeutics in cancer treatment
(Elsevier Masson s.r.l., 2023-05-05)
Several proteins and peptides have therapeutic potential and can be used for cancer therapy. By binding to cell surface receptors and other indicators uniquely linked with or overexpressed on tumors compared to healthy ...
Untangle the mystery behind DS-associated AD � Is APP the main protagonist?
(Elsevier Ireland Ltd, 2023-04-07)
Amyloid precursor protein profusion in Trisomy 21, also called Down Syndrome (DS), is rooted in the genetic determination of Alzheimer's disease (AD). With the recent development in patient care, the life expectancy of DS ...
Onco-Pathogen Mediated Cancer Progression and Associated Signaling Pathways in Cancer Development
(MDPI, 2023-05-28)
Infection with viruses, bacteria, and parasites are thought to be the underlying cause of about 8�17% of the world�s cancer burden, i.e., approximately one in every five malignancies globally is caused by an infectious ...
Epicardial adipose tissue and cardiac lipotoxicity: A review
(Elsevier Inc., 2023-07-05)
Epicardial adipose tissue (EAT) has morphological and physiological contiguity with the myocardium and coronary arteries, making it a visceral fat deposit with some unique properties. Under normal circumstances, EAT exhibits ...
The incidence of male breast cancer: from fiction to reality - correspondence
(NLM (Medline), 2023-05-24)
[No abstract available]
The Implication of Mechanistic Approaches and the Role of the Microbiome in Polycystic Ovary Syndrome (PCOS): A Review
(MDPI, 2023-01-16)
As a complex endocrine and metabolic condition, polycystic ovarian syndrome (PCOS) affects women�s reproductive health. These common symptoms include hirsutism, hyperandrogenism, ovulatory dysfunction, irregular menstruation, ...
Heavy Metal and Metalloid Contamination in Food and Emerging Technologies for Its Detection
(Multidisciplinary Digital Publishing Institute (MDPI), 2023-01-09)
Heavy metal and metalloid poisoning in the environment and food has piqued the public�s interest since it poses significant hazards to the ecological system and human health. In food, several metals, including cadmium (Cd), ...
A Systematic Role of Metabolomics, Metabolic Pathways, and Chemical Metabolism in Lung Cancer
(MDPI, 2023-02-08)
Lung cancer (LC) is considered as one of the leading causes of cancer-associated mortalities. Cancer cells� reprogrammed metabolism results in changes in metabolite concentrations, which can be utilized to identify a ...