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Concurrent Assessment of Oxidative Stress and MT-ATP6 Gene Profiling to Facilitate Diagnosis of Autism Spectrum Disorder (ASD) in Tamil Nadu Population
(Springer, 2023-03-27)
Autism spectrum disorder (ASD) is a neurodevelopmental disability that causes social impairment, debilitated verbal or nonverbal conversation, and restricted/repeated behavior. Recent research reveals that mitochondrial ...
Type 2 Diabetes (T2DM) and Parkinson�s Disease (PD): a Mechanistic Approach
(Springer, 2023-04-28)
Growing evidence suggest that there is a connection between Parkinson�s disease (PD) and insulin dysregulation in the brain, whilst the connection between PD and type 2 diabetes mellitus (T2DM) is still up for debate. ...
Evolving strategies and application of proteins and peptide therapeutics in cancer treatment
(Elsevier Masson s.r.l., 2023-05-05)
Several proteins and peptides have therapeutic potential and can be used for cancer therapy. By binding to cell surface receptors and other indicators uniquely linked with or overexpressed on tumors compared to healthy ...
Advantages of mesenchymal stem cell over the other stem cells
(Elsevier GmbH, 2023-05-09)
A stem cell is a particular group of cells that has the extraordinary potential to convert within the body into particular cell types. They are used to regenerate tissues and cells in the body that have been damaged or ...
Cloning, expression and in vitro validation of chimeric multi epitope vaccine candidate against visceral leishmaniasis infection
(Elsevier Inc., 2023-04-11)
Visceral Leishmaniasis or Kala-Azar is one of the most severe and deadly neglected tropical disease caused by the Leishmania parasite. A few number of vaccines are going through different phases in clinical trial but failing ...
Untangle the mystery behind DS-associated AD � Is APP the main protagonist?
(Elsevier Ireland Ltd, 2023-04-07)
Amyloid precursor protein profusion in Trisomy 21, also called Down Syndrome (DS), is rooted in the genetic determination of Alzheimer's disease (AD). With the recent development in patient care, the life expectancy of DS ...
HPV-associated cancers: insights into the mechanistic scenario and latest updates
(Springer, 2023-06-26)
Cancer and related diseases are the second leading cause of death worldwide. The human papillomavirus (HPV) is an infectious agent that can be spread mainly through sexual contact and has been linked to several malignancies ...
Onco-Pathogen Mediated Cancer Progression and Associated Signaling Pathways in Cancer Development
(MDPI, 2023-05-28)
Infection with viruses, bacteria, and parasites are thought to be the underlying cause of about 8�17% of the world�s cancer burden, i.e., approximately one in every five malignancies globally is caused by an infectious ...
Artificial intelligence in heavy metals detection: Methodological and ethical challenges
(Elsevier B.V., 2023-07-02)
Heavy metals (HMs) are metallic substances. They enter biotic and abiotic systems through natural and human activities. These HMs have an impact on the atmosphere, soil, and groundwater, and they also affect all living ...
A deeper understanding about the role of uranium toxicity in neurodegeneration
(Academic Press Inc., 2023-06-15)
Natural deposits and human-caused releases of uranium have led to its contamination in the nature. Toxic environmental contaminants such as uranium that harm cerebral processes specifically target the brain. Numerous ...