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The regulatory roles of long non-coding RNAs in the development of chemoresistance in breast cancer
(Impact Journals LLC, 2017)
Chemoresistance is one of the major hurdles in the treatment of breast cancer, which limits the effect of both targeted and conventional therapies in clinical settings. Therefore, understanding the mechanisms underpinning ...
Genetic and epigenetic markers in colorectal cancer screening: recent advances
(Taylor & Francis, 2017)
Introduction: Colorectal cancer (CRC) is a heterogenous disease which develops from benign intraepithelial lesions known as adenomas to malignant carcinomas. Acquired alterations in Wnt signaling, TGFβ, MAPK pathway genes ...
Microbial xylanases and their industrial application in pulp and paper biobleaching: a review
(Springer Verlag, 2017)
Xylanases are hydrolytic enzymes which cleave the ?-1, 4 backbone of the complex plant cell wall polysaccharide xylan. Xylan is the major hemicellulosic constituent found in soft and hard food. It is the next most abundant ...
H2 O2 sensing through electrochemically deposited thionine coated ITO thin film
(CMB Association Publications, 2017)
Progression and initiation of different diseases including pulmonary diseases, alzheimer’s and tumors are linked with the oxidative stress, an important cause of cell damage. Different antioxidant enzymes are involved in ...
The emerging role of long non-coding RNA in gallbladder cancer pathogenesis
(Elsevier B.V., 2017)
Gallbladder cancer (GBC) is the most common and aggressive form of biliary tract carcinoma with an alarmingly low 5-year survival rate. Despite its high mortality rate, the underlying mechanisms of GBC pathogenesis are not ...
Role of sphingosine-1-phosphate in mast cell functions and asthma and its regulation by non-coding RNA
(Frontiers Media S.A., 2017)
Sphingolipid metabolites are emerging as important signaling molecules in allergic diseases specifically asthma. One of the sphingolipid metabolite, sphingosine-1-phosphate (S1P), is involved in cell differentiation, ...
Larval mid-gut responses to sub-lethal dose of cry toxin in lepidopteran pest Achaea janata
(Frontiers Media S.A., 2017)
The lack of homogeneity in field application of Bacillus thuringiensis formulation often results in ingestion of sub-lethal doses of the biopesticide by a fraction of pest population and there by promotes the toxin tolerance ...
Stage-specific functions of Semaphorin7A during adult hippocampal neurogenesis rely on distinct receptors
(Nature Publishing Group, 2017)
The guidance protein Semaphorin7A (Sema7A) is required for the proper development of the immune and nervous systems. Despite strong expression in the mature brain, the role of Sema7A in the adult remains poorly defined. ...
Cloning, characterization and transmission blocking potential of midgut carboxypeptidase A in Anopheles stephensi
(Elsevier B.V., 2017)
Transmission-blocking vaccines (TBV) interrupt malaria parasite transmission and hence form an important component for malaria eradication. Mosquito midgut exopeptidases such as aminopeptidase N & carboxypeptidase B have ...
Fat body remodeling in Spodoptera litura F. (Lepidoptera: Noctuidae) during postembryonic development2017
(Association for Advancement of Entomology, 2017)
During insect metamorphosis, larval structures including fat body are replaced by the adult ones. This process involves lysosomal enzyme-mediated remodeling of fat body. The objective of this study is to characterize the ...