Search
Now showing items 31-40 of 43
Bioinformatic Analysis Of Four Proteins Differentially Expressed In A Colon Cancer Cell Line Treated With Rice Callus Suspension Culture
(Central University of Punjab, 2018)
Plant callus extracts have been shown to have effective anticancer activity. In a previous study, cancer cells (colon cancer cell line SW620), was treated with rice callus suspension culture and certain proteins were found ...
Nutrient Analysis of Two Chickpea Cultivars Grown in Local Soil and Treated with Plant Growth Promoting Bacteria from Bathinda Region
(Central University of Punjab, 2018)
The bacteria found near plant roots are known to affect plant and soil health. Several important characteristics, such as biological nitrogen fixation, phosphate solubilization and production of siderophores and phytohormones ...
Estimation of heavy metals in human blood samples- To evaluate immunotoxic correlation with health risk in local population of Malwa region of Punjab
(Central University of Punjab, 2018)
Elements play a significant role in the human body for growth, development, and metabolism. But there are certain heavy metals which adversely affect the various processes of the biological system. A certain amount of ...
Oxidative stress stimulates invasive potential in rat C6 and human U-87 MG glioblastoma cells via activation and cross-talk between PKM2, ENPP2 and APE1 enzymes.
(Springer, 2018)
Maintaining genomic integrity is essential for cell survival and viability. Reactive oxygen species (ROS) overproduction results in oxidative stress leading to the genomic instability via generation of small base lesions ...
Identification of Curcuma longa phytochemicals as a novel inhibitor of proteins involved in Allergic Rhinitis
(Central University of Punjab, 2018)
Histamine and other chemical mediators play crucial role in the disease development condition of allergic rhinitis. Allergic rhinitis is a mild or severe allergic condition due to the interaction of allergens with the IgE ...
Identification of novel indole based heterocycles as selective estrogen receptor modulator.
(Elsevier, 2018)
In the present study, we have designed and synthesized indole derivatives by coalescing the indole nucleus with chromene carbonitrile and dihydropyridine nucleus. Two compounds 5c and 6d were selected from series I and II ...
Downregulation of Bcr-Abl oncogene in Chronic Myeloid Leukemia (CML) by microRNAs in case of Imatinib resistance
(ASIAN PACIFIC JOURNAL OF HEALTH SCIENCES, 2018)
The well-known myeloproliferative malignancy, chronic myeloid leukemia (CML), causes due to the formation of
short and modified Philadelphia chromosome having the Bcr-Abl oncogene. Many therapeutic approaches have been
made ...
Inflammasome activation and regulation during Helicobacter pylori pathogenesis
(Elsevier, 2018)
Helicobacter pylori is a leading cause of gastric cancer worldwide, its type four secretary toxin CagA is cited to be primarily responsible for it. Other virulence factors such as urease, VacA, HopQ, BabA and SabA are ...
Design, synthesis and biological evaluation of novel indole-benzimidazole hybrids targeting estrogen receptor alpha (ER-?)
(Elsevier Masson SAS, 2018)
In the course of efforts to develop novel selective estrogen receptor modulators (SERMs), indole-benzimidazole hybrids were designed and synthesised by fusing the indole nucleus with benzimidazole. All the compounds were ...