Browsing Zoology-Research Publications by Title
Now showing items 122-141 of 173
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Onco-Pathogen Mediated Cancer Progression and Associated Signaling Pathways in Cancer Development
(MDPI, 2023-05-28)Infection with viruses, bacteria, and parasites are thought to be the underlying cause of about 8�17% of the world�s cancer burden, i.e., approximately one in every five malignancies globally is caused by an infectious ... -
Ontogeny of TR?1 expression in the mouse testis and epididymis during postnatal development
(John Wiley and Sons Inc, 2022-06-27)Thyroid hormone (T3) acts on the testis via thyroid hormone receptor alpha 1 (TR?1), though the cellular localization of TR?1 in testis remains controversial. Studies on the presence of TR?1 in the epididymis are also ... -
ORGANOPHOSPHATE PESTICIDES PESTER Aβ- INDUCED GENOTOXIC RESPONSES IN CULTURED NEURONAL CELLS: APE1/Ref-1 MEDIATED INTERVENTION
(Central University of Punjab, 2018)Amyloid beta ( ) peptide deposition is the primary cause of neurodegeneration in reasons deposition, but the actual cause is not apparent. Several reports point towards the role of pesticides in the AD pathogenesis, ... -
Oxidative stress and inflammation in cardiovascular diseases: Two sides of the same coin
(Springer India, 2015)Globally, the major cause of long- term disability and death is an ?epidemiologic transition? from infectious diseases and malnutrition complications to non-communicable chronic diseases like cardiovascular disease (CVD), ... -
Oxidative stress stimulates invasive potential in rat C6 and human U-87 MG glioblastoma cells via activation and cross-talk between PKM2, ENPP2 and APE1 enzymes.
(Springer, 2018)Maintaining genomic integrity is essential for cell survival and viability. Reactive oxygen species (ROS) overproduction results in oxidative stress leading to the genomic instability via generation of small base lesions ... -
Path of Silibinin from diet to medicine: A dietary polyphenolic flavonoid having potential anti-cancer therapeutic significance
(Academic Press, 2020-10-29)In the last few decades, targeting cancer by the use of dietary phytochemicals has gained enormous attention. The plausible reason and believe or mind set behind this fact is attributed to either lesser or no side effects ... -
Peculiar sleep features in sympatric species may contribute to the temporal segregation
(Springer Science and Business Media Deutschland GmbH, 2022-10-22)Sleep is conserved in the animal kingdom and plays a pivotal role in the adaptation of species. Sleep in Drosophila melanogaster is defined as any continuous 5 min of quiescence, shows a�prominent siesta, and consolidated ... -
Phytochemical Ginkgolide B Attenuates Amyloid-? amage and Altered Cellular Responses in Human Neuroblastoma SH-SY5Y Cells
(IOS Press, 2017)Oxidative stress is an upsurge in reactive oxygen/nitrogen species (ROS/RNS), which aggravates damage to cellular components viz. lipids, proteins, and nucleic acids resulting in impaired cellular functions and neurological ... -
Phytochemical Ginkgolide B Attenuates Amyloid- 1 - 42 Induced Oxidative Damage and Altered Cellular Responses in Human Neuroblastoma SH-SY5Y Cells
(IOS Press, 2017)Oxidative stress is an upsurge in reactive oxygen/nitrogen species (ROS/RNS), which aggravates damage to cellular components viz. lipids, proteins, and nucleic acids resulting in impaired cellular functions and neurological ... -
Phytochemical ginkgolide b protects cultured neuroblastoma SH-SY5Y cells against a?(25-35) induced oxidative stress responses by maintaining the mitochondrial integrity
(Rasayan Journal of Chemistry, c/o Dr. Pratima Sharma, 2020)Alzheimer�s disease is associated with oxidative stress induced by accumulation of A? peptide, by disrupting the mitochondrial function. In this study, the oxidative stress responses induced by A?(25-35) and protective ... -
Phytochemicals as Potential Therapeutics for SARS-CoV-2�Induced Cardiovascular Complications: Thrombosis and Platelet Perspective
(Frontiers Media S.A., 2021-04-26)After gaining entry through ACE2 aided by TMPRSS2, the SARS-CoV-2 causes serious complications of the cardiovascular system leading to myocarditis and other myocardial injuries apart from causing lung, kidney and brain ... -
Plasmodium's journey through the Anopheles mosquito: A comprehensive review
(Elsevier B.V., 2020-12-17)The malaria parasite has an extraordinary ability to evade the immune system due to which the development of a malaria vaccine is a challenging task. Extensive research on malarial infection in the human host particularly ... -
Platelet-derived microvesicles activate human platelets via intracellular calcium mediated reactive oxygen species release
(Academic Press Inc., 2022-08-28)Platelet-derived microvesicles (PMVs) are the most abundant microvesicles in circulation, originating from blood platelets via membrane blebbing. PMVs act as biological cargo carrying key molecules from platelets, including ... -
Platelet-derived microvesicles induce intracellular calcium mobilization in human platelets
(John Wiley and Sons Inc, 2023-08-31)Platelet-derived microvesicles (PMVs) represent a significant proportion of microvesicles in circulation and have been linked to various pathophysiological complications. Recent research suggests that PMVs carry significant ... -
Plausible Role of Mitochondrial DNA Copy Number in Neurodegeneration�a Need for Therapeutic Approach in Parkinson�s Disease (PD)
(Springer, 2023-07-31)Parkinson�s disease (PD) is an advancing age-associated progressive brain disorder which has various diverse factors, among them mitochondrial dysfunction involves in dopaminergic (DA) degeneration. Aging causes a rise in ... -
Probing interaction of atherogenic lysophosphatidylcholine with functionalized graphene nanosheets: theoretical modelling and experimental validation
(Springer Science and Business Media Deutschland GmbH, 2023-09-09)Context: The potential of graphene derivatives for theranostic applications depends on their compatibility with cellular and biomolecular components. Lysophosphatidylcholine (LPC), a lipid component present in oxidized ... -
Pseudomonas aeruginosa quorum sensing molecule N-3-oxo-dodecanoyl-L-homoserine lactone activates human platelets through intracellular calcium-mediated ROS generation
(Elsevier GmbH, 2018)Pseudomonas aeruginosa, an opportunistic pathogen release N-3-oxo-dodecanoyl-L-homoserine lactone (3-oxo-C12HSL) and N-butyryl-L-homoserine lactone (C4-HSL) quorum sensing (QS) molecules to regulate various virulence factors ... -
Pseudomonas aeruginosa quorum sensing molecule N-3-oxo-dodecanoyl-Lhomoserine lactone activates human platelets through intracellular calciummediated ROS generation
(Elsevier, 2018)Pseudomonas aeruginosa, an opportunistic pathogen release N-3-oxo-dodecanoyl-l-homoserine lactone (3-oxo-C12HSL) and N-butyryl-l-homoserine lactone (C4-HSL) quorum sensing (QS) molecules to regulate various virulence factors ... -
Quantification and optimization of clot retraction in washed human platelets by Sonoclot coagulation analysis
(John Wiley and Sons Inc, 2021-10-07)Introduction: Clot retraction is a pivotal process for haemostasis, where platelets develop a contractile force in fibrin meshwork and lead to the increased rigidity of clot. The pathophysiological alteration in contractile ... -
Rapid Arc-SBRT: Non-Invasive Immune Adjuvant for Advanced Stage Non-Small Cell Lung Carcinoma
(Bentham Science Publishers, 2021-03-23)In conjunction with radio-chemotherapy, pulmonary resection is recommended for early-stage non-small-cell lung carcinoma but not for advanced-stage NSCLC patients having high-grade metastatic lesions. In these cases, the ...