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Evaluating anti-oxidant potential of ganoderic acid A in STAT 3 pathway in prostate cancer
(Springer Netherlands, 2016)
Evaluating anti-oxidant potential of Ganoderic acid A in STAT 3 pathway in Prostate cancer. Molecular docking and ADMET activities of different isoforms of ganoderic acid on STAT 3 pathway were performed by Maestro 9.6 ...
Missing link between microRNA and prostate cancer
(Springer Netherlands, 2016)
MicroRNAs are the non-coding RNAs which regulate endogenous gene expression in animal and plant cells. Alterations in the level of micro-ribonucleic acids (miRNAs) involving the deletions, overexpression, mutations, ...
Ganoderic Acid A Targeting β-Catenin in Wnt Signaling Pathway: In Silico and In Vitro Study
(Springer, 2016)
Wnt signaling pathways are the group of signaling transduction controlling the embryonic development, cell proliferation, cell migration, cell fate specification, and body axis pattern. Nuclear accumulation of β-catenin ...
Triterpenes in cancer: significance and their influence
(Springer Netherlands, 2016)
Natural products are enriched with numerous compounds with a broad spectrum of therapeutics indication suggesting the role of functional moieties as a core pharmacophore. This review highlights the role of triterpene in ...
Ganoderic acid targeting multiple receptors in cancer: in silico and in vitro study
(Springer Netherlands, 2016)
Receptor tyrosine kinases (RTKs) are transmembrane high-affinity surface receptors responsible for cell migration, adhesion, apoptosis, metabolism, and cell proliferation activities in various cancers. Minute aberration ...