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In silico screening and molecular interaction studies of tetrahydrocannabinol and its derivatives with acetylcholine binding protein
(Bentham Science Publishers B.V., 2018)
Background: Alzheimer’s disease (AD) is the fourth largest cause of death among people over 65 years of age. Accumulation of β-amyloid and cholinergic deficiency are two prominent pathological descriptions for AD.
Objective: ...
OXIDATIVE STRESS INDUCED CELL PROLIFERATION AND DNA REPAIR MECHANISMS IN GLIOBLASTOMA CELLS: ROLE OF ENPP2 AND APE1
(Central University of Punjab, 2018)
Glioblastoma Multiforme (GBM) is a grade IV, most frequent, and invasive devastating brain tumor with poor prognosis, even with the advancement of multimodal therapies, patients have survival period of less than 15 months. ...
ANALYSIS OF MICRORNA SIGNATURES AS BIOMARKER TO INVESTIGATE INTERLINK BETWEEN TYPE 2 DIABETES AND BREAST CANCER
(Central University of Punjab, 2018)
Type 2 diabetes and breast cancer are two heterogeneous, multifactorial, chronic health problems involving several overlapping risk factors. Studies have suggested that type 2 diabetes is associated with 10-20% excessive ...
GANODERMA LUCIDUM, A POTENTIAL THERAPEUTIC MODULATOR IN CANCER SIGNALING: IN SILICO AND IN VITRO ANALYSIS
(Central University of Punjab, 2018)
DNA barcode-based identification and comparative anti-cancer effects of different species of brown seaweed Sargassum C. Agardh of Indian coasts
(Central University of Punjab, 2018)
Sargassum C. Agardh is a ubiquitous, multicellular brown seaweed that represents the most species-rich genus of the brown algal order Fucales, with more than 500 species reported worldwide. The present study aimed to ...
Macromolecular crowding on Dynamics and Thermodynamic Stability of Heme Proteins
(Elsevier, 2018)
Structural and molecular properties extracted from circular dichroism (CD), tryptophanfluorescence and 1-anilino-8-napthalene sulfonate (ANS) binding experiments suggest that the high concentration of synthetic crowding ...
Factors Defining the Effects of macromolecularcrowding on dynamics and thermodynamics stability of heme proteins in-vitro
(Elsevier, 2018)
The role of crowding agents on structure and activities of heme proteins has been established. Analysis of kinetic and thermodynamic parameters measured for CO-dissociation reaction of natively-folded carbonmonoxycytochrome ...
Flavonoid accumulation as adaptation response in plants during abiotic stresses
(Routledge Taylor & Franchis Group, 2018)
Flavonoids are secondary plant metabolites and are required for the proper growth and development of plants. Flavonoids also contribute by providing protection against adverse environmental conditions due to their antioxidant ...
Pseudomonas: A Major Bacteria in Heavy Metal Contaminated Soil of South-West Punjab.
(http://www.isebindia.com/, 2018)