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Biological/Biosimilar Drugs: A New Hope for Better and Low Cost Treatment
(Juniper Publishers, 2016)
Biological and biosimilar drugs
Medicines that are derived from living cells/organisms are
known as biological medicines. They consist of of highly complex
molecular entities difficult to characterize. Certain degree ...
Association of MTHFR (C677T) Gene Polymorphism With Breast Cancer in North India
(Sage, 2016)
Background
Breast cancer is one of the most common malignancies in women and is associated with a variety of risk factors. The functional single-nucleotide polymorphism (SNP) C677T in the gene encoding 5,10-methylenetet ...
D Allele Frequency in Insertion/Deletion Polymorphism of the Angiotensin Converting Enzyme (ACE) Gene is Associated with Development of Breast Cancer Risk in Indian Women
(Bentham Science, 2016)
Aims: Breast cancer is the second most common cancer in the world and, by far, the most frequent cancer among women. Scientific literature has hypothesized the association of ACE I/D polymorphism with breast cancer for ...
Novel Wnt and Notch Signaling Natural Inhibitors as Double Edged Sword Against Cancer War: An approach Towards Computer Based Drug Design
(Juniper Publishers, 2016)
Cancer is a group of disease characterized by the uncontrolled growth and spread of abnormal cells which may lead to death. According to
a report by GLOBOCAN the number of new cancer cases would increase to 19.3 million ...
Geminin as an Emerging Anticancer Drug Target
(Juniper Publishers, 2016)
For normal cell division, one time replication origin firing is
mandatory. The mutual interaction and levels of Cdt1 and geminin
(GMNN) proteins are known to be involved in this regulatory
mechanism. Imbalance between these ...
Geminin a multi task protein involved in cancer pathophysiology and developmental process: A review
(Elsevier B.V., 2016)
DNA replicates in a timely manner with each cell division. Multiple proteins and factors are involved in the initiation of DNA replication including a dynamic interaction between Cdc10-dependent transcript (Cdt1) and Geminin ...