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Understanding human thiol dioxygenase enzymes: structure to function and biology to pathology
(Wiley, 2017)
Amino acid metabolism is a significant metabolic activity in humans, especially of sulphur-containing amino acids, methionine and cysteine (Cys). Cys is cytotoxic and neurotoxic in nature; hence, mammalian cells maintain ...
A short review on cross-link between pyruvate kinase (PKM2) and Glioblastoma Multiforme
(Springer, 2021-03-02)
Pyruvate kinase (PK) catalyzes the last irreversible reaction of glycolysis pathway, generating pyruvate and ATP, from Phosphoenol Pyruvate (PEP) and ADP precursors. In mammals, four different tissue-specific isoforms (M1, ...
Herbal Remedies for Improving Cancer Treatment Through Modulation of Redox Balance
(Springer Singapore, 2022-09-28)
The redox modulation induced by oxidative stress is one of the major cause of the metabolic and inflammatory disorders including cancer. The reactive oxygen species (ROS) produced by various sources in the cell shift the ...
A short review on cross-link between pyruvate kinase (PKM2) and Glioblastoma Multiforme
(Springer, 2021-03-02)
Pyruvate kinase (PK) catalyzes the last irreversible reaction of glycolysis pathway, generating pyruvate and ATP, from Phosphoenol Pyruvate (PEP) and ADP precursors. In mammals, four different tissue-specific isoforms (M1, ...