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Oncogenic metabolic reprogramming in breast cancer: focus on signaling pathways and mitochondrial genes
(Springer, 2023-05-11)
Oncogenic metabolic reprogramming impacts the abundance of key metabolites that regulate signaling and epigenetics. Metabolic vulnerability in the cancer cell is evident from the Warburg effect. The research on metabolism ...
Genetic variations in tumor-suppressor miRNA-encoding genes and their target genes: focus on breast cancer development and possible therapeutic strategies
(Springer Science and Business Media Deutschland GmbH, 2023-04-24)
MicroRNAs (miRNAs) negatively affect gene expression by binding to their specific mRNAs resulting in either mRNA destruction or translational repression. The aberrant expression of various miRNAs has been associated with ...
Comprehensive analysis of culture conditions governing differentiation of MSCs into articular chondrocytes
(Newlands Press Ltd, 2023-05-18)
Treatment of osteoarthritic patients requires the development of morphologically and mechanically complex hyaline cartilage at the injury site. A tissue engineering approach toward differentiating mesenchymal stem cells ...