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Drug-metabolizing enzymes: role in drug resistance in cancer
(Springer, 2020)
Although continuous researches are going on for the discovery of new chemotherapeutic agents, resistance to these anticancer agents has made it really difficult to reach the fruitful results. There are many causes for this ...
Dihydropyrimidine dehydrogenase in the metabolism of the anticancer drugs
(Springer Verlag, 2019)
Cancer caused by fundamental defects in cell cycle regulation leads to uncontrolled growth of cells. In spite of the treatment with chemotherapeutic agents of varying nature, multiple resistance mechanisms are identified ...