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An Overview on Biological Activities of Oxazole, Isoxazoles and 1,2,4-Oxadiazoles Derivatives
(Springer Nature, 2022-03-07)
Heterocyclic compounds containing the oxazole, isoxazole and oxadiazoles rings have received significant consideration as they perform like a link between life sciences and chemical sciences. In the past few years, the ...
An Overview on Biological Activities of 1,2,3-Triazole Derivatives
(Springer Nature, 2022-03-07)
Among the nitrogen-embedded heterocycles, 1,2,3-triazoles derivatives are widely explored and earned considerable attraction in pharmaceutical industry and academics. 1,2,3-Triazoles have attracted significant consideration ...
An Overview on Biological Evaluation of Tetrazole Derivatives
(Springer Nature, 2022-03-07)
Tetrazoles are distinguished by a five-membered, doubly unsaturated ring which consists of four nitrogen and one carbon atom with a molecular formula CN4H2, which have a wide range of medicinal activity and potential role ...
An Overview on Biological Activity of Benzimidazole Derivatives
(Springer Nature, 2022-03-07)
Benzimidazole moiety plays a key role in variety of heterocyclic scaffolds which derive the biological functioning of essential molecules. Because of the skeletal resemblance with the naturally appearing nucleotides, ...
Overview on Biological Activities of Pyrazole Derivatives
(Springer Nature, 2022-03-07)
Pyrazoles are appraised as medicinally significant heterocyclic nuclei that exhibit a widespread spectrum of biological properties. The existence of pyrazole derivatives as pharmacophore in distinct remedial divisions like ...
Overview on Biological Activities of Imidazole Derivatives
(Springer Nature, 2022-03-07)
Imidazole and its derivatives are one of the most important and widely used heterocycles in medicinal chemistry, natural products, and synthetic chemicals. Because of the imidazole ring's unique structural features, imidazole ...
P(III)-Mediated Cascade C-N/C-S Bond Formation: A Protocol towards the Synthesis of N,S-Heterocycles and Spiro Compounds
(Wiley-VCH Verlag, 2020-11-20)
A P(III)-mediated entry towards construction of C?N/C?S bond has been devised. The developed heterocyclization method was exercised for the synthesis of a diverse range of N,S-heterocycles and related spiro molecules. ...
Efficient approach towards the polysubstituted 4h-pyran hybrid quinolone derivatives and subsequent copper-catalyzed hydroxylation of haloarenes
(Japan Institute of Heterocyclic Chemistry, 2021-03-16)
A proficient and feasible approach towards polysubstituted quinolone conjugated 4H-pyrans has been elucidated. The illustrated phenomenon concern with the base-mediated multicomponent reaction and subsequent copper-catalyzed ...
Synthesis of pyrazolo[4,3-c]quinolines and the C-C bond cleavage during reductive cyclization
(Japan Institute of Heterocyclic Chemistry, 2021-02-26)
An efficient synthesis of o-nitrophenyl tethered pyrazole-4-carbaldehydes was achieved via Vilsmeier-Haack formylation of hydrazone derivatives which were subjected to Claisen-Schmidt condensation and Morita-Baylis-Hillman ...
Potassium tert-Butoxide-Mediated Synthesis of 2-Aminoquinolines from Alkylnitriles and 2-Aminobenzaldehyde Derivatives
(John Wiley and Sons Inc, 2022-12-08)
KOtBu mediates the reaction between 2-amino arylcarbaldehydes and benzyl/alkyl cyanides toward the expeditious formation of 2-aminoquinolines under transition-metal-free conditions. The described transformation proceeds ...