Browsing Pharmaceutical Sciences and Natural Products-Research Publications by Author "Jain, Akhlesh K."
Now showing items 1-3 of 3
-
In silico docking of anti cancerous drugs with ?-cyclodextrin polymer as a prominent approach to improve the bioavailability
Jain, Akhlesh K.; Mishra, Keerti; Thareja, Suresh (Bentham Science Publishers, 2020-10-14)Background: ?-Cyclodextrin, a cyclic oligosaccharides having 7 macrocyclic rings of glucose subunits usually linked together by ?-1,4 glycosidic bond, bears characteristic chemical structure, with an exterior portion as ... -
In silico molecular interaction studies of chitosan polymer with aromatase inhibitor: Leads to letrozole nanoparticles for the treatment of breast cancer
Mishra, Keerti; Verma, Sant K.; Ratre, Pooja; Banjare, Laxmi; Jain, Abhishek; Thareja, Suresh; Jain, Akhlesh K. (Bentham Science Publishers, 2020-08-26)Background: It takes a lot more studies to evaluate the molecular interaction of nanoparticles with the drug, their drug delivery potential and release kinetics. Thus, we have taken in silico and in vitro approaches into ... -
Polymeric nanoparticles of aromatase inhibitors: A comprehensive review
Mishra, Keerti; Ratre, Pooja; Thareja, Suresh; Jain, Akhlesh K. (Bentham Science Publishers, 2020-09-29)Being the second most frequent cancer, breast cancer is emerging worldwide with an alarming rate, specifically in post-menopausal women. Targeted drug delivery has been in the focus for the successful treatment of breast ...