Browsing Pharmaceutical Sciences and Natural Products-Research Publications by Author "Jaitak, Vikas"
Now showing items 1-20 of 54
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Anticancer activity of essential oils: A review
Bhalla, Yashika; Gupta, Vinay Kumar; Jaitak, Vikas (2013)Natural essential oil constituents play an important role in cancer prevention and treatment. Essential oil constituents from aromatic herbs and dietary plants include monoterpenes, sesquiterpenes, oxygenated monoterpenes, ... -
Antimicrobial and repellent activity of the essential oils of two lamiaceae cultivated in Western Himalaya
Stappen, Iris; Ali, Abbas; Tabanca, Nurhayat; Khan,Ikhlas A.; Wanner, J�rgen; Gochev, Velizar K.; Singh, Virendra; Lal, Brij; Jaitak, Vikas; Kaul, Vijay K.; Schmidt, Erich; Jirovetz, Leopold; Stappen, I.; Ali, A.; Tabanca, N.; Khan, I.A.; Wanner, J.; Gochev, V.K.; Singh, V.; Lal, B.; Jaitak, V.; Kaulh, V.K.; Schmidt, E.; Jirovetz, L. (Bentham Science Publishers B.V., 2015)The essential oils of two Lamiaceae cultivated in Western Himalaya were examined on their antimicrobial, biting deterrent as well as larvicidal activity. Additionally their odors are described and their chemical compositions ... -
Chemical Composition and Biological Activity of Essential Oils from Wild Growing Aromatic Plant Species of Skimmia laureola and Juniperusmacropoda from Western Himalaya
Stappena,Iris; Tabanca, Nurhayat; Ali, Abbas; Wedge, David E.; Wanner, J�rgen; Kaul, Vijay K.; Lal, Brij; Jaitak, Vikas; Gochev, Velizar K.; Schmidt, Erich; Jirovetz, Leopold (NPC (Natural Product Communication), 2015)The Himalayan region is very rich in a great variety of medicinal plants. In this investigation the essential oils of two selected species are described for their antimicrobial and larvicidal as well as biting deterrent ... -
Chemical composition and biological activity of essential oils of dracocephalum heterophyllum benth And Hyssopus officinalis L Collected wild from Western Himalay
Stappena, Iris; Wannerb Jürgen; Tabanca, Nurhayat; Wedge, David E.; Ali, Abbas; Kaul, Vijay K.; Lal, Brij; Jaitak, Vikas; Gochev, Velizar K.; Schmidt, Erich; Jirovetz, Leopold (Sage, 2015)The essential oils of two representatives of the Lamiaceae, Dracocephalum heterophyllum Benth. and Hyssopus officinalis L., are described for their antifungal, antibacterial, larvicidal and inect biting deterrent activities. ... -
Chemical composition and biological effects of Artemisia essential oils from Western Himalaya
Stappen, Iris; Wanner, J, rgen; Tabanca, Nurhayat; Wedge, David E.; Ali, Abbas; Khan, Ikhlas A.; Kaul, Vijay K.; Lal, Brij; Jaitak, Vikas; Gochev, Velizar; Girova, Tania; Stoyanova, Albena; Schmidt, Erich; Jirovetz, Leopold (Theime, 2014)Artemisia species possess pharmacological properties that are used for medical purposes worldwide. In this paper, the essential oils from the aerial parts of Artemisia nilagirica and Artemisia maritima from the western ... -
Chemical composition and biological effects of artemisia maritima and artemisia nilagirica essential oils from wild plants of Western Himalaya
Stappen, Iris; Wanner, J, rgen; Tabanca, Nurhayat; Wedge, David E.; Ali, Abbas; Khan, Ikhlas A.; Kaul, Vijay K.; Lal, Brij; Jaitak, Vikas; Gochev, Velizar; Girova, Tania; Stoyanova, Albena; Schmidt, Erich; Jirovetz, Leopold; Stappen, I.; Wanner, J.; Tabanca, N.; Wedge, D.E.; Ali, A.; Khan, I.A.; Kaul, V.K.; Lal, B.; Jaitak, V.; Gochev, V.; Girova, T.; Stoyanova, A.; Schmidt, E.; Jirovetz, L. (Georg Thieme Verlag, 2014)Artemisia species possess pharmacological properties that are used for medical purposes worldwide. In this paper, the essential oils from the aerial parts of Artemisia nilagirica and Artemisia maritima from the western ... -
Coumarin Derivatives as Anticancer Agents for Lung Cancer Therapy: A Review.
Kumar, Manvendra; Singla, Ramit; Jandriyal, Jyoti; Jaitak, Vikas (Bentham Science, 2018)Background: The prevalence of lung cancer is 14% among the newly diagnosed cancer cases worldwide. Currently, the number of drugs that are in clinical practice is having a high prevalence of side effect and multidrug ... -
Coumarins as anticancer agents: A review on synthetic strategies, mechanism of action and SAR studies
Thakur, Anuradha; Singla, Ramit; Jaitak, Vikas (Elsevier Masson SAS, 2015)Abstract Coumarins are fused benzene and pyrone ring systems which prompt biological investigation to assess their potential therapeutic significance. It possesses immeasurable anticancer potential with minimum side effects ... -
Design, Synthesis and Evaluation of Indole Based Compounds as Putative Anticancer Agents
Singla, Ramit (Central University of Punjab, 2018)In the course of efforts to develop new chemotherapeutic agent for targeting breast cancer, indole-benzimidazole, indole-xanthendione, indole-chromene carbonitrile and indole-dihydropyridine derivatives were computationally ... -
Drug target strategies in breast cancer treatment: Recent developments
Mayank; Jaitak, Vikas; Mayank, Jaitak, V. (Bentham Science Publishers B.V., 2014)Breast cancer (BC) is the leading cause of death among women all over the world. Estrogen receptor (ER) based therapy is one of the major approaches to target BC and is associated with various problems such as primary as ... -
Drug Targeting Strategies in Breast Cancer Treatment
Mayank; Jaitak, Vikas (Bentham Science, 2014)Breast cancer (BC) is the leading cause of death among women all over the world. Estrogen receptor (ER) based therapy is one of the major approaches to target BC and is associated with various problems such as primary as ... -
Effectiveness of Selective Estrogen Receptor Modulators in Breast Cancer Therapy: An Update
Das, Agnidipta; Lavanya, Kanamarlapudi Joshna; Nandini; Kaur, Kamalpreet; Jaitak, Vikas (Bentham Science Publishers, 2022-10-06)Background: Breast cancer is considered to be 2nd most common cancer sub-type investigated worldwide. It is mainly prevalent in postmenopausal women. Estrogen Receptor (ER) is a primary transcription factor for the survival ... -
Engagement of phytoestrogens in breast cancer suppression: Structural classification and mechanistic approach
Tanwar, Ankur Kumar; Dhiman, Neha; Kumar, Amit; Jaitak, Vikas (Elsevier Masson s.r.l., 2020-11-24)Cancer is the world's devastating disease, and breast cancer is the most common reason for the death of women worldwide. Many synthetic drugs and medications are provided with their beneficial actions, but all of these ... -
Erratum: Chemical Composition and Biological Effects of Artemisia maritima and Artemisia nilagirica Essential Oils from Wild Plants of Western Himalaya (Planta Medica (2014) 80:13 (1079-1087) DOI: 10.1055/s-0034-1382957)
Stappen, I.; Wanner, J.; Tabanca, N.; Wedge, D.E.; Ali, A.; Khan, I.A.; Kaul, V.K.; Lal, B.; Jaitak, Vikas; Gochev, V.; Girova, T.; Stoyanova, A.; Schmidt, E.; Jirovetz, L. (Georg Thieme Verlag, 2014)[No abstract available] -
Essential Oils: An Impending Substitute of Synthetic Antimicrobial Agents to Overcome Antimicrobial Resistance
Pal, Rajinder; Rana, Abhilash; Jaitak, Vikas (Bentham Science, 2019)ntimicrobial resistance (AMR) is an emerging problem in the world that has a significant impact on our society. AMR made conventional drugs futile against microorganisms and diseases untreatable. Plant-derived medicines ... -
Essential Oils: New Perspectives in Human Health and Wellness.
Firenzuoli, Fabio; Jaitak, Vikas; Horvath, Gyorgyi; Bassole, Imael Henri Nestor; Setzer,William N.; Gori, Luigi (Hindawi, 2014)Essential oils are natural products, derived from aromatic plants, traditionally used all over the world for disinfection, as anti-inflammatory, relaxing, and stimulating substances, and with potential and modern exploitation ... -
Flavonoids as P-glycoprotein inhibitors for multidrug resistance in cancer: an in-silico approach
Kumar, Amit; Kalra, Sourav; Jangid, Kailash; Jaitak, Vikas (Taylor and Francis Ltd., 2022-09-19)Cancer has become a leading cause of mortality due to non-communicable diseases after cardiovascular disease worldwide and is increasing day by day at a daunting pace. According to an estimate by 2040 there will be 28.4 ... -
Glycine Catalyzed One-Pot Three-Component Synthesis of Structurally Diverse 2-Amino Substituted Pyran Annulated Heterocycles in Aqueous Ethanol under Refluxed Conditions
Banerjee, Bubun; Kaur, Manmeet; Sharma, Aditi; Singh, Arvind; Priya, Anu; Gupta, Vivek Kumar; Jaitak, Vikas (Bentham Science Publishers, 2022-12-14)Introduction: A facile, convenient and general method has been developed for the one-pot three-component synthesis of structurally diverse 2-amino pyran annulated heterocycles from the reactions of aromatic aldehydes, ... -
Identification of 1,3,4-oxadiazoles as tubulin-targeted anticancer agents: a combined field-based 3D-QSAR, pharmacophore model-based virtual screening, molecular docking, molecular dynamics simulation, and density functional theory calculation approach
Das, Agnidipta; Sarangi, Manaswini; Jangid, Kailash; Kumar, Vijay; Kumar, Amit; Singh, Praval Pratap; Kaur, Kamalpreet; Kumar, Vinod; Chakraborty, Sudip; Jaitak, Vikas (Taylor and Francis Ltd., 2023-09-11)Cancer is one of the most prominent causes of death worldwide and tubulin is a crucial protein of cytoskeleton that maintains essential cellular functions including cell division as well as cell signalling, that makes an ... -
Identification of novel indole based heterocycles as selective estrogen receptor modulator
Singla, Ramit; Prakash, Kunal; Bihari Gupta, Kunj; Upadhyay, Shishir; Dhiman, Monisha; Jaitak, Vikas (Academic Press Inc., 2018)In the present study, we have designed and synthesized indole derivatives by coalescing the indole nucleus with chromene carbonitrile and dihydropyridine nucleus. Two compounds 5c and 6d were selected from series I and II ...