Browsing Pharmaceutical Sciences and Natural Products-Research Publications by Author "Nayyar, Himanshu"

Now showing items 1-2 of 2

    • Pyrimidine containing epidermal growth factor receptor kinase inhibitors: Synthesis and biological evaluation 

      Joshi, Gaurav; Nayyar, Himanshu; Kalra, Sourav; Sharma, Praveen; Munshi, Anjana; Singh, Sandeep; Kumar, Raj (Blackwell Publishing Ltd, 2017)
      Structure-based design and synthesis of pyrimidine containing reversible epidermal growth factor receptor (EGFR) inhibitors 1a?d are reported. The compounds (1a?d) inhibited the EGFR kinase activity in vitro with IC50 range ...

    • Pyrimidine-fused derivatives: Synthetic strategies and medicinal attributes 

      Joshi, Gaurav; Nayyar, Himanshu; Alex, Jimi Marin; Vishwakarma, Gajendra S.; Mittal, Sunil; Kumar, Raj (Bentham Science Publishers B.V., 2016)
      Pyrimidine-fused derivatives traits the inextricable part of DNA and RNA, exhibit indispensable role in numerous biological processes, possessing momentous chemical and biological importance. Pyrimidine-condensed derivatives ...