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Developing our knowledge of the quinolone scaffold and its value to anticancer drug design
(Taylor and Francis Ltd., 2023-08-18)
Introduction: The quinolone scaffold is a bicyclic benzene-pyridinic ring scaffold with nitrogen at the first position and a carbonyl group at the second or fourth position. It is endowed with a diverse spectrum of ...
Flavonoids as promising anticancer agents: an in silico investigation of ADMET, binding affinity by molecular docking and molecular dynamics simulations
(Taylor and Francis Ltd., 2022-09-27)
Cancer is one of the most concerning diseases to humankind. Various treatment strategies are being employed for its treatment, out of which use of natural products is an essential one. Flavonoids have proven to be promising ...
Boron in cancer therapeutics: An overview
(Elsevier Inc., 2023-10-17)
Boron has become a crucial weapon in anticancer research due to its significant intervention in cell proliferation. Being an excellent bio-isosteric replacement of carbon, it has modulated the anticancer efficacy of various ...