RSS 1.0Biochemistry and Microbial Sciences-Master Dissertation
Recent Submissions
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Identification of some novel natural inhibitors of proteins in the life cycle of the malarial parasite
(Central University of Punjab, 2018)Antimalarial phytoconstituents were identified and analysed.We studied receptor based molecular docking of protein drug targets( Plasmepsin 2 (1lf2),HSP90 (3k60), PfATPase ( 1u5n), Human orotidine 5 - decarboxylase domain ... -
Extraction And Identification Of Secondary Metabolites Produced By Soil Actinomycetes And Their Biochemical Characterization
(Central University of Punjab, 2018)The worldwide use of antibiotics has rapidly increased since the discovery of penicillin in 1928 by Alexander Fleming, for treating terrible bacterial diseases. But in due course of time, over-consumption of antibiotics ... -
Identification of Novel Natural Inhibitors Of Proteins Involved In Cancer Cell Stemness
(Central University of Punjab, 2018)Cancer stem cells (CSCs) are a small subpopulation of cells identified in a variety of tumors that are capable of self-renewal, differentiation and have the unique property to evade radiotherapy and chemotherapy. CSCs are ... -
Isolation And Determination Of Antibiotic Susceptibility Of Enterococcus Faecalis From Malwa Region
(Central University of Punjab, 2018)About 20 isolates of Enterococcus faecalis is isolated from six different places of Malwa region. They include isolate from Animal waste soil, Agriculture soil, Sewage soil and public place soil also. Isolation of Enterococcus ... -
Antibacterial and Anticancer property of bioactive secondary metabolites from Actinomycetes isolated from different regions of Himachal Pradesh
(Central University of Punjab, 2018)The prime objective of the present work is to isolate, characterize and purify soil microbes and to know about their antibacterial and anticancer properties. Soil samples were obtained from different locations in Dharamsala, ... -
Assessment of Extract of Syzygium cumini Against Doxorubicin Induced Cardiotoxicity
(Central University of Punjab, 2018)For the past four decades, doxorubicin (DOX) has been used to treat cancer, mainly solid tumours and haematological malignancies. However, clinical community is greatly concerned regarding the administration of this as DOX ... -
Production and Optimization of Lovastatin by Microbial Fermentation using Aspergillus terreus
(Central University of Punjab, 2018)In the recent times, the fungus Aspergillus (A.) terreus has been highly popularized regarding its domination for the production of the "crackerjack" drugs known as statins, particularly lovastatin. The aim of this research ... -
Role of Plant Growth Promoting Bacteria in Improving the Quality of Marginal Soil for Multiple Purposes
(Central University of Punjab, 2018)Degrading quality of soil by the presence of xenobiotics or change in the natural environment of soil is of great concern. One of them is heavy metal pollution of soil. With increasing population, sustainable food production ... -
Expression, Purification and Kinetic Characterization of Lactate Dehydrogenase of Lactic Acid Bacteria and ProB of Bacillus subtilis
(Central University of Punjab, 2018)Lactate dehydrogenase is very well known for its role in glucose metabolism in Lactic Acid Bacteria (LAB). These bacteria are widely used in the industrial and research areas. LAB use NADH as a cofactor to produce lactate ... -
Role of Helicobacter pylori Enriched Media in Inducing Oxidative Stress in Human Cell lines
(Central University of Punjab, 2018)Helicobacter pylori is a gram-negative, helical, microaerophilic bacterium which colonizes the human gastrointestinal tract. Vacuolating cytotoxin A (VacA) is one of the major virulent factors. Reactive oxygen species (ROS) ... -
Estimation of heavy metals in human blood samples- To evaluate immunotoxic correlation with health risk in local population of Malwa region of Punjab
(Central University of Punjab, 2018)Elements play a significant role in the human body for growth, development, and metabolism. But there are certain heavy metals which adversely affect the various processes of the biological system. A certain amount of ... -
Bioinformatic Analysis Of Four Proteins Differentially Expressed In A Colon Cancer Cell Line Treated With Rice Callus Suspension Culture
(Central University of Punjab, 2018)Plant callus extracts have been shown to have effective anticancer activity. In a previous study, cancer cells (colon cancer cell line SW620), was treated with rice callus suspension culture and certain proteins were found ... -
Comparison of Pyruvate Kinase of different species of Lactic Acid Bacteria
(Central University of Punjab, 2018)Pyruvate kinase (PK) is an important allosterically regulated enzyme that connects Glycolysis from the primary energy to cellular metabolism. It catalyzes the last step of Glycolysis by producing one mole of energy in the ... -
Characterization of Hexaploid Wheat Protein on the Basis of their Date of Release in Indian sub- continent
(Central University of Punjab, 2018)Wheat is the third most grown cereal worldwide. The storage proteins of wheat represent an important source of food and energy and are also involved in the determination of bread wheat quality. These gluten proteins are ... -
Nutrient Analysis of Two Chickpea Cultivars Grown in Local Soil and Treated with Plant Growth Promoting Bacteria from Bathinda Region
(Central University of Punjab, 2018)The bacteria found near plant roots are known to affect plant and soil health. Several important characteristics, such as biological nitrogen fixation, phosphate solubilization and production of siderophores and phytohormones ... -
Understanding Immune-etiology of Psoriasis: An autoimmune disease
(Central University of Punjab, 2018)Psoriasis is a chronic inflammatory autoimmune disease. Disease etiology is understood in terms of altered crosstalk between skin keratinocytes and immune cell infiltrates, specifically T cells leading to the development ... -
Identification of natural inhibitors of proteins involved in the pathology of Parkinson's disease
(Central University of Punjab, 2018)Parkinson's disease (PD) is a progressive neurodegenerative disorder caused due to the lack of dopamine in the brain. Different drug therapies are available for PD showing excellent efficiency, but most of them are cost ... -
In Silico Identification of Novel Natural Inhibitors Of Carbohydrate Metabolic Pathway In Cancer Cells
(Central University of Punjab, 2018)Carbohydrate metabolism in cancer cells is linked to the 'Warburg Effect' which states that, under aerobic conditions, cancer cells metabolize approximately ten fold more glucose to lactate in a given time than normal ... -
Identification of Curcuma longa phytochemicals as a novel inhibitor of proteins involved in Allergic Rhinitis
(Central University of Punjab, 2018)Histamine and other chemical mediators play crucial role in the disease development condition of allergic rhinitis. Allergic rhinitis is a mild or severe allergic condition due to the interaction of allergens with the IgE ...
