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Exploring microRNA profiles for circadian clock and flowering development regulation in Himalayan Rhododendron
(Elsevier, 2018)
miRNA is a non-coding, yet crucial entity in remodeling the genetic architecture. Rhododendron arboreum of Himalayas grows and even flower under fluctuating climate. sRNA from leaves of vegetative and reproductive periods ...
S961, a biosynthetic insulin receptor antagonist, downregulates insulin receptor expression & suppresses the growth of breast cancer cells
(Indian Council of Medical Research (ICMR), 2018)
Background & objectives: Insulin resistance associated with hyperinsulinaemia and overexpression of insulin receptors (IRs) have been intricately linked to the pathogenesis and treatment outcomes of the breast carcinoma. ...
RNAseq-based phylogenetic reconstruction of Taxaceae and Cephalotaxaceae
(Wiley, 2018)
Taxaceae and Cephalotaxaceae are the two economically important conifer families. Over the years there has been much controversy over the issue of merging these families. The position of Amentotaxus and Torreya is also ...
Antioxidant potential of ganoderic acid in Notch-1 protein in neuroblastoma
(Springer, 2018)
Neuroblastoma is a childhood tumor arising from developing a sympathetic nervous system and causes around 10% of pediatric tumors. Despite advancement in the use of sophisticated techniques in molecular biology, neuroblastoma ...
Macromolecular crowding-induced molten globule states of the alkali pH-denatured proteins
(Elsevier B.V., 2018)
Structural and molecular properties extracted from circular dichroism (CD), tryptophan fluorescence and 1-anilino-8-napthalene sulfonate (ANS) binding experiments suggest that the high concentration of synthetic crowding ...
Vitex negundo and its medicinal value
(Springer, 2018)
Natural products are rich in several potent bioactive compounds, targeting complex network of proteins involved in various diseases. Vitex negundo (VN), commonly known as “chaste tree”, is an ethnobotanically important ...
Pivotal role of bZIPs in amylose biosynthesis by genome survey and transcriptome analysis in wheat (Triticum aestivum L.) mutants
(Nature Publishing Group, 2018)
Starch makes up 70% of the wheat grain, and is an important source of calories for humans, however, the overconsumption of wheat starch may contribute to nutrition-associated health problems. The challenge is to develop ...
Comparative Analysis of Metabolites in Contrasting Chickpea Cultivars
(Central University of Punjab, 2018)
Phenolics are the major class of plant secondary metabolites. Among half of the
plant phenolics are the flavonoids. The production of these metabolites induces
during stresses and thus helps the plant to cope with the ...
Identification Of Ganoderic Acids And Derivatives From Fruiting Bodies Of Ganoderma Lucidum
(Central University of Punjab, 2018)
Ganoderic acids and other bioactive triterpene metabolites from crude extract of wood decaying fungus Ganoderma lucidum from two different hosts Acacia and Azadirachta were to be isolated as proposed. The method for ...
Amelioration of Salinity stress in Chickpea (Cicer arietinum L.) variety PBG5 through foliar spray of Ascorbic acid
(Central University of Punjab, 2018)
Chickpea (C. arietinum L.) is the second most important legume crop
sown as a winter crop in northern parts of India, and its productivity is
constraint by several abiotic stress, and sat stress is one of the
important ...