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CRP Gene (1059G>C) Polymorphism and Its Plasma Levels in Ischemic Stroke and Hemorrhagic Stroke in a South Indian Population
(Springer New York LLC, 2014)
In the present study, we evaluated the association of 1059G>C polymorphism in C-reactive protein (CRP) gene with the risk of ischemic and hemorrhagic strokes. We did not find a significant association of this polymorphism ...
E-selectin gene (S128R) polymorphism in hemorrhagic stroke: Comparison with ischemic stroke
(Elsevier Ireland Ltd, 2014)
Increasing evidence suggests that genetic variation in inflammatory genes plays a pivotal role in pathogenesis of stroke. The aim of the present study was to evaluate the association of E-selectin S128R polymorphism with ...
Association of Xmn1 -158 γG variant with severity and HbF levels in β-thalassemia major and sickle cell anaemia
(Springer Netherlands, 2014)
Haemoglobinopathies including ?-thalassemia and sickle cell anaemia (SCA) are considered to be classical monogenic diseases. There is considerable clinical variability between patients inheriting identical ?-globin mutations. ...
Toca-1 is suppressed by p53 to limit breast cancer cell invasion and tumor metastasis
(BioMed Central Ltd., 2014)
Introduction: Transducer of Cdc42-dependent actin assembly-1 (Toca-1) recruits actin regulatory proteins to invadopodia, and promotes breast tumor metastasis. Since metastatic breast tumors frequently harbor mutations in ...
Oxidative stress and inflammation in diabetic complications
(Hindawi Publishing Corporation, 2014)
Apolipoprotein C3 gene polymorphisms in Southern Indian patients with nonalcoholic fatty liver disease
(Springer, 2014)
Aim
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease in the world today. A previous study has suggested an association of apolipoprotein C3 (APOC3) gene variants with the risk of NAFLD in Asian ...
Genetics of idiopathic generalized epilepsy: An overview
(Neurology Society of India, 2014)
Idiopathic generalized epilepsy (IGE) is a common type of epilepsy. Strong support for a genetic role in IGE comes from twin and family studies. Several subtypes of IGE have been reported but families often have members ...