Browsing Biochemistry and Microbial Sciences-Research Publications by Author "Upadhyay, Shishir"
Now showing items 1-2 of 2
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Design, synthesis and biological evaluation of novel indole-xanthendione hybrids as selective estrogen receptor modulators
Singla, Ramit; Gupt,a Kunj Bihari; Upadhyay, Shishir; Dhiman Monisha; Jaitak Vikas (Elsevier Ltd, 2018)Ground breaking clinical therapeutic advances in the treatment of breast cancer (BC) is the introduction of selective estrogen receptor modulators (SERMs). We have expeditiously designed and synthesized indole-xanthendione ... -
Identification of novel indole based heterocycles as selective estrogen receptor modulator.
Singla, Ramit; Prakash, Kunal; Gupta Kunj Bihari; Upadhyay, Shishir; Dhiman, Monisha; Jaitak, Vikas (Elsevier, 2018)In the present study, we have designed and synthesized indole derivatives by coalescing the indole nucleus with chromene carbonitrile and dihydropyridine nucleus. Two compounds 5c and 6d were selected from series I and II ...