Browsing Pharmacology-Research Publications by Issue Date
Now showing items 1-20 of 122
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Protocols in apoptosis identification and affirmation
(Elsevier, 2020-10-16)Protocols are set of predefined written procedural documents that offer guidance or specifications for performing the experiments and its implementation. They are an essential component of good laboratory practice (GLP) ... -
Is highly expressed ACE 2 in pregnant women �a curse� in times of COVID-19 pandemic?
(Elsevier Inc., 2020-10-28)Angiotensin-converting enzyme 2 (ACE 2) is a membrane-bound enzyme that cleaves angiotensin II (Ang II) into angiotensin (1�7). It also serves as an important binding site for SARS-CoV-2, thereby, facilitating viral entry ... -
Neuroprotective effect of nerolidol in traumatic brain injury associated behavioural comorbidities in rats
(Oxford University Press, 2020-11-26)Traumatic brain injury (TBI) is an insult to the brain from an external mechanical force, leading to temporary/permanent secondary injuries, i.e. impairment of cognitive, physical, and psycho-social functions with altered ... -
Neuroprotection through G-CSF: recent advances and future viewpoints
(Springer Science and Business Media Deutschland GmbH, 2021-01-02)Granulocyte-colony stimulating factor (G-CSF), a member of the cytokine family of hematopoietic growth factors, is 19.6�kDa glycoprotein which is responsible for the proliferation, maturation, differentiation, and survival ... -
Animal models of attention-deficit hyperactivity disorder (ADHD)
(John Wiley and Sons Inc, 2021-01-15)Attention-deficit hyperactivity disorder (ADHD) is a heterogeneous neuropsychiatric disorder characterized by three primary symptoms hyperactivity, attention deficit, and impulsiveness, observed in both children and adults. ... -
The beneficial effect of rice bran extract against rotenone-induced experimental parkinson�s disease in rats
(Bentham Science Publishers, 2021-02-12)Background: Neurodegenerative diseases have become an increasing cause of various disabilities worldwide, followed by aging, including Parkinson�s disease (PD). Parkinson�s disease is a degenerative brain disorder distinguished ... -
Can bilirubin nanomedicine become a hope for the management of COVID-19?
(Churchill Livingstone, 2021-02-15)Bilirubin has been proven to possess significant anti-inflammatory, antioxidant and antiviral activities. Recently, it has been postulated as a metabolic hormone. Further, moderately higher levels of bilirubin are positively ... -
Novel pharmacological approaches for diabetic complications
(Nova Science Publishers, Inc., 2021-03-24)Diabetes is a chronic illness characterized by uncontrolled hyperglycemia, disturbances in carbohydrate, and lipid and protein metabolism due to impaired function of insulin-secreting pancreatic ?-cell, insulin action or ... -
Emerging role of non?coding RNA in health and disease
(Springer, 2021-04-21)Human diseases have always been a significant turf of concern since the origin of mankind. It is cardinal to know the cause, treatment, and cure for every disease condition. With the advent and advancement in technology, ... -
Decorin as a possible strategy for the amelioration of COVID-19
(Churchill Livingstone, 2021-05-20)Coronavirus pandemic has emerged as an extraordinary healthcare crisis in modern times. The SARS-CoV-2 novel coronavirus has high transmission rate, is more aggressive and virulent in comparison to previously known ... -
Role of vitamins and minerals as immunity boosters in COVID-19
(Springer Science and Business Media Deutschland GmbH, 2021-06-10)Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) known as coronavirus disease (COVID-19), emerged in Wuhan, China, in December 2019. On March 11, 2020, it was declared a global pandemic. As the world grapples ... -
Therapeutic Strategies Targeting Signaling Pathways in Lung Cancer
(Springer Nature, 2021-07-02)Recent knowledge of the role of signaling pathways and their underlying mechanisms in the pathogenesis of several diseases may lead to the development of therapeutic strategies. In the recent time, several drug molecules ... -
Various Cellular and Molecular Axis Involved in the Pathogenesis of Asthma
(Springer Nature, 2021-07-02)Asthma is a chronic inflammatory disease described by impaired lung function, airway hyperresponsiveness, episodic wheezing, and dyspnea. Asthma prevalence has risen drastically, and it is estimated that more than 339 ... -
Rhino-orbital-cerebral-mucormycosis in COVID-19: A systematic review
(Wolters Kluwer Medknow Publications, 2021-08-18)Since the onset of COVID-19 pandemic, parallel opportunistic infections have also been emerging as another disease spectrum. Among all these opportunistic infection, mucormycosis has become a matter of concern with its ... -
Antinociceptive activity of standardized extract of Bacopa monnieri in different pain models of zebrafish
(Elsevier Ireland Ltd, 2021-08-19)Ethnopharmacological relevance: Bacopa monnieri L. (Scrophulariaceae) is commonly known as Brahmi and traditionally used as a neuroprotective herbal medicine. Recently, Bacopa monnieri exhibited significant therapeutic ... -
Neurobiology of traumatic brain injury
(Taylor and Francis Ltd., 2021-09-06)Traumatic brain injury (TBI) involves structural damage to the brain regions causing death or disability in patients with lifelong sufferings. Accidental injuries to the brain, besides structural damage, if any, cause ... -
Quercetin Exhibits ?7nAChR/Nrf2/HO-1-Mediated Neuroprotection Against STZ-Induced Mitochondrial Toxicity and Cognitive Impairments in Experimental Rodents
(Springer, 2021-09-23)The objective of the present study was to investigate the ?7nAChR-mediated Nrf2-dependant protective activity against streptozotocin (STZ)-induced brain mitochondrial toxicity in Alzheimer�s disease (AD)-like rats. STZ ... -
Methionine as a double-edged sword in health and disease: Current perspective and future challenges
(Elsevier Ireland Ltd, 2021-10-25)Methionine is one of the essential amino acids and plays a vital role in various cellular processes. Reports advocate that methionine restriction and supplementation provide promising outcomes, and its regulation is critical ... -
Recent Advances in Molecular Pathways and Therapeutic Implications Targeting Mitochondrial Dysfunction for Alzheimer�s Disease
(Springer, 2021-11-02)Alzheimer�s disease (AD) is a neurodegenerative disorder which leads to mental deterioration due to aberrant accretion of misfolded proteins in the brain. According to mitochondrial cascade hypothesis, mitochondrial ... -
Biomedical applications of polysaccharide nanoparticles for chronic inflammatory disorders: Focus on rheumatoid arthritis, diabetes and organ fibrosis
(Elsevier Ltd, 2021-11-22)Polysaccharides are biopolymers distinguished by their complex secondary structures executing various roles in microorganisms, plants, and animals. They are made up of long monomers of similar type or as a combination of ...
