Search
Now showing items 1-9 of 9
Gene therapy: Comprehensive overview and therapeutic applications
(Elsevier Inc., 2022-02-03)
Gene therapy is the product of man's quest to eliminate diseases. Gene therapy has three facets namely, gene silencing using siRNA, shRNA and miRNA, gene replacement where the desired gene in the form of plasmids and viral ...
Antimicrobial and anti-viral effects of selenium nanoparticles and selenoprotein based strategies: COVID-19 and beyond
(Editions de Sante, 2023-06-08)
Deficiency of selenium (Se) has been described in a significant number of COVID-19 patients having a higher incidence of mortality, which makes it a pertinent issue to be addressed clinically for effective management of ...
Advances in therapeutic applications of silver nanoparticles
(Elsevier Ireland Ltd, 2023-06-01)
Nanotechnology is one of the most appealing area for developing new applications in biotechnology and medicine. For decades, nanoparticles have been extensively studied for a variety of biomedical applications. Silver has ...
Evolution of Zebrafish as a Novel Pharmacological Model in Endocrine Research
(Springer Nature, 2022-05-30)
Zebrafish is a powerful platform in the modern era of phenotype-based drug discovery and eminent vertebrate model to study disease progression and its pathophysiology. Zebrafish possess several advantages over rodent model ...
Biomedical applications of polysaccharide nanoparticles for chronic inflammatory disorders: Focus on rheumatoid arthritis, diabetes and organ fibrosis
(Elsevier Ltd, 2021-11-22)
Polysaccharides are biopolymers distinguished by their complex secondary structures executing various roles in microorganisms, plants, and animals. They are made up of long monomers of similar type or as a combination of ...
A comprehensive overview of CRISPR/Cas 9 technology and application thereof in drug discovery
(John Wiley and Sons Inc, 2022-09-21)
Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-Cas technology possesses revolutionary potential to positively affect various domains of drug discovery. It has initiated a rise in the area of genetic ...
Decorin as a possible strategy for the amelioration of COVID-19
(Churchill Livingstone, 2021-05-20)
Coronavirus pandemic has emerged as an extraordinary healthcare crisis in modern times. The SARS-CoV-2 novel coronavirus has high transmission rate, is more aggressive and virulent in comparison to previously known ...
Can bilirubin nanomedicine become a hope for the management of COVID-19?
(Churchill Livingstone, 2021-02-15)
Bilirubin has been proven to possess significant anti-inflammatory, antioxidant and antiviral activities. Recently, it has been postulated as a metabolic hormone. Further, moderately higher levels of bilirubin are positively ...
Apoptosis and Pharmacological Therapies for Targeting Thereof for Cancer Therapeutics
(MDPI, 2022-04-08)
Apoptosis is an evolutionarily conserved sequential process of cell death to maintain a homeostatic balance between cell formation and cell death. It is a vital process for normal eukaryotic development as it contributes ...