Search
Now showing items 1-9 of 9
Targeting Mitochondria as a Novel Disease-Modifying Therapeutic Strategy in Cancer
(Springer Nature, 2022-01-31)
Mitochondria are important for the metabolism of energy, regulation of apoptosis and cell signaling. Overproduction of reactive oxidation species (ROS) in mitochondria is one of the indications of cancer cells; moreover, ...
Gut microbiota dysbiosis and Huntington's disease: Exploring the gut-brain axis and novel microbiota-based interventions
(Elsevier Inc., 2023-06-24)
Huntington's disease (HD) is a complex progressive neurodegenerative disorder affected by genetic, environmental, and metabolic factors contributing to its pathogenesis. Gut dysbiosis is termed as the alterations of ...
Protective role of natural products and bioactive compounds in multiple sclerosis
(Elsevier, 2023-06-16)
Multiple sclerosis (MS), a chronic multifactorial disease characterized by progressive demyelination and neurodegeneration, is rising rapidly in young adults. The pathology of the disease is not yet understood completely. ...
Therapeutic Strategies Targeting Signaling Pathways in Lung Cancer
(Springer Nature, 2021-07-02)
Recent knowledge of the role of signaling pathways and their underlying mechanisms in the pathogenesis of several diseases may lead to the development of therapeutic strategies. In the recent time, several drug molecules ...
Targeting Mitochondria as a Novel Disease-Modifying Therapeutic Strategy in Cancer
(Springer Singapore, 2022-09-28)
Mitochondria are essential for the metabolism of energy, regulation of apoptosis, and cell signaling. Overproduction of reactive oxidation species (ROS) in mitochondria is one of the indications of cancer cells. Moreover, ...
Emerging role of non?coding RNA in health and disease
(Springer, 2021-04-21)
Human diseases have always been a significant turf of concern since the origin of mankind. It is cardinal to know the cause, treatment, and cure for every disease condition. With the advent and advancement in technology, ...
Various Cellular and Molecular Axis Involved in the Pathogenesis of Asthma
(Springer Nature, 2021-07-02)
Asthma is a chronic inflammatory disease described by impaired lung function, airway hyperresponsiveness, episodic wheezing, and dyspnea. Asthma prevalence has risen drastically, and it is estimated that more than 339 ...
Dysregulated autophagy: A key player in the pathophysiology of type 2 diabetes and its complications
(Elsevier B.V., 2023-02-14)
Autophagy is essential in regulating the turnover of macromolecules via removing damaged organelles, misfolded proteins in various tissues, including liver, skeletal muscles, and adipose tissue to maintain the cellular ...
Advancing Cancer Immunotherapy: The Potential of mRNA Vaccines As a Promising Therapeutic Approach
(John Wiley and Sons Inc, 2023-10-04)
mRNA vaccines have long been recognized for their ability to induce robust immune responses. The discovery that mRNA vaccines may also contribute to antitumor immunity has made them a promising therapeutic approach against ...