Browsing Chemistry-Research Publications by Title
Now showing items 71-90 of 146
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Imine/amide-imidazole conjugates derived from 5-amino-4-cyano-N1-substituted benzyl imidazole: Microwave-assisted synthesis and anticancer activity via selective topoisomerase-II-? inhibition
(Elsevier Ltd, 2015)Microwave-accelerated synthesis and anticancer activity of novel imine/amide-imidazole conjugates derived from 5-amino-4-cyano-N1-substituted benzyl imidazole against a panel of seven cancer cell lines are reported for the ... -
In situ reductive regeneration of zerovalent iron nanoparticles immobilized on cellulose for atom efficient Cr(vi) adsorption
(Royal Society of Chemistry, 2015)Zerovalent iron nanoparticles (nZVI) (11.8 - 0.2% w/w) immobilized on microcrystalline cellulose (C-nZVI) were synthesized and studied for Cr(vi) sorption. The material showed good atom economy for Cr(vi) adsorption (562.8 ... -
Insulin resistance induces a segmental difference in thoracic and abdominal aorta: Differential expression of AT1 and AT2 receptors
(2012)Objectives: The study was pursued to understand and compare the vascular reactivity to angiotensin II (Ang II) and its receptor expression in thoracic and abdominal aorta under insulin resistance. Methods: Vascular reactivity ... -
Interfacial design of gold/silver core-shell nanostars for plasmon-enhanced photocatalytic coupling of 4-aminothiophenol
(Royal Society of Chemistry, 2021-10-02)Chemical reactions under mild conditions mediated by localized surface plasmon resonance (LSPR) of metals have emerged as a functional research field. In the present study, we report an interfacial designing procedure for ... -
Interfacial Engineering of CuCo2S4/g-C3N4Hybrid Nanorods for Efficient Oxygen Evolution Reaction
(American Chemical Society, 2021-07-29)Altering the morphology of electrochemically active nanostructured materials could fundamentally influence their subsequent catalytic as well as oxygen evolution reaction (OER) performance. Enhanced OER activity for ... -
Investigation of Indole-3-piperazinyl Derivatives as Potential Antidepressants: Design, Synthesis, In-Vitro, In-Vivo and In-Silico Analysis
(John Wiley and Sons Inc, 2021-11-03)Depression is declared the second leading cause of disability worldwide. Recently, cases of depression have increased significantly in adolescents, young adults as well as in elder population. Monoamine oxidase-A (MAO-A) ... -
Invitro anti-mutagenic potential of potentilla fulgens: A western himalayan plant
(Informatics Publishing Limited, 2014)Invitro anti-mutagenic potential of different extracts/fractions of Potentilla fulgens has been made by an Ames histidine reversion assay using TA98 and TA100 tester strains of Salmonella typhimurium against the direct-acting ... -
Iodine-Catalysed Synthesis of ?-Carboline Tethered ?-Amino Amidines Through Ugi-Type Multicomponent Reaction
(John Wiley and Sons Inc, 2022-09-15)A simple and efficient iodine catalysed protocol has been unfolded for the synthesis of novel ?-carboline C1-linked ?-amino amidines via one-pot assembly of 1-formyl ?-carbolines (Kumujian C analogues), anilines and ... -
KI-assisted Sulfur Activation/Insertion/Denitration Strategy towards Dual C?S Bond Formation for One-pot Synthesis of ?-Carboline-tethered 2-Acylbenzothiophenes
(John Wiley and Sons Inc, 2021-12-13)A simple and efficient KI promoted sulfur activation-insertion/de-nitration strategy has been developed for the synthesis of ?-carboline C1 tethered 2-acylbenzothiophenes via one-pot assembly of 1-acetyl ?-carbolines (an ... -
A Literature Review of Pulmonary Arterial Hypertension (PAH)
(Bentham Science Publishers, 2022-02-18)In 1891, German doctor E. Romberg was the first to report PAH. It is widespread throughout the world, but it is particularly problematic in India and other developing countries. Pulmonary arterial hypertension (PAH) is ... -
Macromolecular crowding on Dynamics and Thermodynamic Stability of Heme Proteins
(Elsevier, 2018)Structural and molecular properties extracted from circular dichroism (CD), tryptophanfluorescence and 1-anilino-8-napthalene sulfonate (ANS) binding experiments suggest that the high concentration of synthetic crowding ... -
Macromolecular crowding-induced molten globule states of the alkali pH-denatured proteins
(Elsevier B.V., 2018)Structural and molecular properties extracted from circular dichroism (CD), tryptophan fluorescence and 1-anilino-8-napthalene sulfonate (ANS) binding experiments suggest that the high concentration of synthetic crowding ... -
Mechanism of Iron Integration into LiMn1.5Ni0.5O4for the Electrocatalytic Oxygen Evolution Reaction
(American Chemical Society, 2022-09-14)Spinel-type LiMn1.5Ni0.5O4 has been paid temendrous consideration as an electrode material because of its low cost, high voltage, and stabilized electrochemical performance. Here, we demonstrate the mechanism of iron (Fe) ... -
Mechanisms of tubulin binding ligands to target cancer cells: Updates on their therapeutic potential and clinical trials
(Bentham Science Publishers B.V., 2017)Background: A number of chemically diverse substances bind to the tubulin and inhibit cell proliferation by disrupting microtubule dynamics. There are four binding sites for the ligands binding to the tubulin; taxane/epothilone ... -
Metal- and Hazardous Reagent-Free Transamidation Process: the NH2OH?HCl Promoted N-Formylation and N-Acylation Reaction under Solvent-Less Conditions
(Taylor and Francis Ltd., 2023-09-14)An efficient transamidation process has been described under solvent-less conditions. The transformation has been accomplished by employing NH2OH?HCl as a reagent and amines as substrates. The developed method is achieved ... -
Metal- And Solvent-Free Multicomponent Decarboxylative A3-Coupling for the Synthesis of Propargylamines: Experimental, Computational, and Biological Investigations
(American Chemical Society, 2020)Decarboxylative A3-coupling of ortho-hydroxybenzaldehydes, secondary amines, and alkynoic acids is performed under catalyst and solvent-free conditions. The developed methodology provided a waste-free method for the synthesis ... -
Metal-Free Direct Access to N-Sulfonyl Amidines from Sulfonamides and Secondary Amines Involving Tandem C-N Bond Formations
(American Chemical Society, 2022-08-17)We report a mild and efficient metal-free one-pot procedure for the synthesis of N-sulfonyl amidines via the direct reaction of sulfonamides with secondary amines without using any additives. A wide range of substrates ... -
Morita-Baylis-Hillman reaction of 3-formyl-9H-pyrido[3,4-b]indoles and fluorescence studies of the products
(Beilstein-Institut Zur Forderung der Chemischen Wissenschaften, 2022-07-26)?-Carboline is a privileged class of the alkaloid family and is associated with a broad spectrum of biological properties. 3-Formyl-9H-pyrido[3,4-b]indole is a such potent precursor belonging to this family which can be ... -
Multi-Target-Directed Ligands as an Effective Strategy for the Treatment of Alzheimer�s Disease
(Bentham Science Publishers, 2021-05-12)Alzheimer�s disease (AD) is a complex neurological disorder and multiple pathological factors are believed to be involved in the genesis and progression of the disease. A number of hypothesis including Acetylcholinesterase, ... -
Nano-Heteroarchitectures of Two-Dimensional MoS2@ One-Dimensional Brookite TiO2 Nanorods: Prominent Electron Emitters for Displays
(American Chemical Society, 2017)We report comparative field electron emission (FE) studies on a large-area array of two-dimensional MoS2-coated one-dimensional (1D) brookite (?) TiO2 nanorods synthesized on Si substrate utilizing hot-filament metal vapor ...